Search Results

Overview

Uniprot ID	F1RQW9
Protein Name	[histone H3]-lysine(9) N-methyltransferase
Gene Name	EHMT2
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
287	SDVAKRRKLNSGGGL

Function

No function data available.

Protein Sequence

10 MRGLPRGRGL 20 LRARGRGRAA 30 PPGSRSRGRG 40 GPHRGRGRPR 50 SLLSLPRAQA 60 SWAPQLPTGL 70 TSPPIPCVPS 80 QGEAPAEMGA 90 LVLEKEPRGA 100 TERVHGSLGD 110 TPRSEEALPK 120 ANPDSLEPAG 130 PSSPASVTVT 140 VGDEGADTPI 150 GATPLIGDEP 160 ENLEGDGDLH 170 GGRILLGHAT 180 KSFPSSPSKG 190 GACPSRAKMS 200 MTGAGKSPPS 210 VQSLAMRLLS 220 MPGAQGAAAA 230 AIPEPPPATA 240 SPEGQPKVHR 250 ARKTMSKPGN 260 GQPPVPEKRP 270 PEVQHFRMSD 280 DVHSLGKVTS 290 DVAKRRKLNS 300 GGGLSEELGS 310 ARGSGDVSLE 320 KGDPGSLEEW 330 ETVVGDDFSL 340 YYDSYSVDER 350 VDSDSKSEVE 360 ALAEQLSEEE 370 EEEEEEEEEE 380 EEEEEEEEEE 390 EEDEESGNQS 400 DRSGSSGRRK 410 AKKKWRKDSP 420 WVKPSRKRRK 430 REPPRAKEPR 440 GVSNDTSSLE 450 TERGFEELPL 460 CSCRMEAPKI 470 DRISERAGHK 480 CMATESVDGE 490 LSGCNAAILK 500 RETMRPSSRV 510 ALMVLCETHR 520 ARMVKHHCCP 530 GCGYFCTAGT 540 FLECHPDFRV 550 AHRFHKACVS 560 QLNGMVFCPH 570 CGEDASEAQE 580 VTIPRDGVTP 590 PAGTAAPAPP 600 PLAQDAGRAD 610 TSQPSARMRG 620 HGEPRRPPCD 630 PLADTIDSSG 640 PSLTLPSGGC 650 LSAVGLPPGP 660 GREALEKALV 670 IQESERRKKL 680 RFHPRQLYLS 690 VKQGELQKVI 700 LMLLDNLDPN 710 FQSDQQSKRT 720 PLHAAAQKGS 730 VEICHVLLQA 740 GANINAVDKQ 750 QRTPLMEAVV 760 NNHLEVARYM 770 VQRGGCVYSK 780 EEDGSTCLHH 790 AAKIGNLEMV 800 SLLLSTGQVD 810 VNAQDSGGWT 820 PIIWAAEHKH 830 IEVIRMLLTR 840 GADVTLTDNE 850 ENICLHWASF 860 TGSAAIAEVL 870 LNARCDLHAV 880 NYHGDTPLHI 890 AARESYHDCV 900 LLFLSRGANP 910 ELRNKEGDTA 920 WDLTPERSDV 930 WFALQLNRKL 940 RLGVGNRAIR 950 TEKIICRDVA 960 RGYENVPIPC 970 VNGVDSEPCP 980 EDYKYISENC 990 ETSTMNIDRN 1000 ITHLQHCTCV 1010 DDCSSSNCLC 1020 GQLSIRCWYD 1030 KDGRLLQEFN 1040 KIEPPLIFEC 1050 NQACSCWRNC 1060 KNRVVQSGIK 1070 VRLQLYRTAK 1080 MGWGVRALQT 1090 IPQGTFICEY 1100 VGELISDAEA 1110 DVREDDSYLF 1120 DLDNKDGEVY 1130 CIDARYYGNI 1140 SRFINHLCDP 1150 NIIPVRVFML 1160 HQDLRFPRIA 1170 FFSSRDIRTG 1180 EELGFDYGDR 1190 FWDIKSKYFT 1200 CQCGSEKCKH 1210 SAEAIALEQS 1220 RLARLDPHPE 1230 LLPELSSLPP VNP

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0000785	chromatin
Cellular Component	GO:0016607	nuclear speck
Cellular Component	GO:0005634	nucleus
Molecular Function	GO:0070742	C2H2 zinc finger domain binding
Molecular Function	GO:0140189	H1-4K26 methyltransferase activity
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity
Molecular Function	GO:0140759	histone H3K56 methyltransferase activity
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity
Molecular Function	GO:0140948	histone H3K9 monomethyltransferase activity
Molecular Function	GO:0002039	p53 binding
Molecular Function	GO:1990841	promoter-specific chromatin binding
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding
Molecular Function	GO:0001222	transcription corepressor binding
Molecular Function	GO:0008270	zinc ion binding
Biological Process	GO:0030261	chromosome condensation
Biological Process	GO:0006346	DNA methylation-dependent constitutive heterochromatin formation
Biological Process	GO:0040029	epigenetic regulation of gene expression
Biological Process	GO:0032259	methylation
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II
Biological Process	GO:0006275	regulation of DNA replication

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.