Search Results

Overview

Uniprot ID	F1RR89
Protein Name	Arginine--tRNA ligase, cytoplasmic
Gene Name	RARS1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
131	MLKTKEQKVNPREIA
17	ARLLQQEKEIKFLTA
193	PAIGANKKVIVDFSS
287	FDTEEEFKKRAYQCV
30	TAEIDRLKNCSCSEA
306	SKNPDILKAWKLICD
309	PDILKAWKLICDVSR
347	DRMNDIVKEFEDRGF
449	GVVLGEDKKKFKTRS
484	LKEKERDKVLTAEEL
492	VLTAEELKAAQTSVA
504	SVAYGCIKYADLSHN
570	KIILDHEKEWKLGRC
60	YRLNILQKSLQAERN

Function

Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1

Protein Sequence

10 MDGLVAACSA 20 RLLQQEKEIK 30 FLTAEIDRLK 40 NCSCSEASSN 50 LERLREENLK 60 LKYRLNILQK 70 SLQAERNKPS 80 KNMINIISGL 90 QEVFGCAIKA 100 AYPDLENPPL 110 IVTPSQQPKF 120 GDYQCNSAMG 130 ISQMLKTKEQ 140 KVNPREIAEN 150 ITKNLPDNEY 160 IEKVEIAGPG 170 FINIHLKKSF 180 VSQQLTNLLV 190 NGVQLPAIGA 200 NKKVIVDFSS 210 PNIAKEMHVG 220 HLRSTIIGES 230 MSRLFEFAGY 240 DVLRINHVGD 250 WGTQFGMLIA 260 HLQDKFPDYL 270 RVSPPIGDLQ 280 AFYKESKKRF 290 DTEEEFKKRA 300 YQCVVLLQSK 310 NPDILKAWKL 320 ICDVSRQEFS 330 KIYEALDISL 340 IERGESFYQD 350 RMNDIVKEFE 360 DRGFVQVDDG 370 RKIVFVPGCP 380 VPLTIVKSDG 390 GYTYDTSDLA 400 TIKQRLFEEK 410 ADMIIYVVDS 420 GQSLHFQAVF 430 GAAQMMGWYD 440 PEVTRVSHAG 450 FGVVLGEDKK 460 KFKTRSGETV 470 RLIDLLEEGL 480 KRSMDKLKEK 490 ERDKVLTAEE 500 LKAAQTSVAY 510 GCIKYADLSH 520 NRLNDYIFSF 530 DKMLDDRGNT 540 AAYLLYAFTR 550 IRSIARLANI 560 DEEMLQKAAR 570 ETKIILDHEK 580 EWKLGRCILR 590 FPEVLQKILD 600 DLFLHTLCDY 610 IYELATTFTE 620 FYDSCYCVEK 630 DRQTGEVLKV 640 NMWRLLLCKA 650 VAAVMAKGFD 660 ILGIKPVQRM

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
Biological Process	GO:0006420	arginyl-tRNA aminoacylation
Cellular Component	GO:0005829	cytosol
Cellular Component	GO:0005634	nucleus
Molecular Function	GO:0004814	arginine-tRNA ligase activity
Molecular Function	GO:0005524	ATP binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.