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Overview

Uniprot IDF1RSJ8
Protein Namepre-rRNA processing protein FTSJ3
Gene NameFTSJ3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
14 VGKSRRDKFYHLAKE
157 RGGCFITKVFRSRDY
182 FRRVQATKPQASRHE
218 FDPKFAFKEVEIQAK
233 TVTELVTKKKPKAEG

Function

Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation

Protein Sequence

10 MGKKGKVGKS 20 RRDKFYHLAK 30 ETGYRSRSAF 40 KLIQLNRRFQ 50 FLQKARALLD 60 LCAAPGGWLQ 70 VAAKFMPVSS 80 LIVGVDLVPI 90 KPLPNVVTLQ 100 EDITTERCRQ 110 ALRKELKTWK 120 VDVVLNDGAP 130 NVGASWVHDA 140 YSQAHLTLMA 150 LRLACDFLGR 160 GGCFITKVFR 170 SRDYQPLLWI 180 FQQLFRRVQA 190 TKPQASRHES 200 AEIFVVCQGF 210 LAPDKVDSKF 220 FDPKFAFKEV 230 EIQAKTVTEL 240 VTKKKPKAEG 250 YAEGDLTLYH 260 RTSVTDFLRA 270 ANPVDFLSKA 280 SEIAIDDEEL 290 ARHPATTEDV 300 RACCQDIRVL 310 GRKELRSLLN 320 WRTKLRRHVA 330 KKLKEQAKAM 340 DISLSSGEEE 350 EGEEEEQAAR 360 ASQQPSKEEE 370 EEEQLNRTLA 380 EMKAQEVAEL 390 KRKKKKLLRE 400 QRKQRERVEL 410 KMDLPGVSIA 420 DEGETGMFSL 430 RTIRGHQLLE 440 EVTQGDMSAA 450 DTFLSDLPSD 460 DIYISDAEED 470 DDDSASLDSD 480 LDPEDLAGVR 490 EPQGLKDQKR 500 VRLAEANDEK 510 EEEGENPLLV 520 PLEEKAVLQE 530 EQASLWFSKD 540 GFSGIEDDAD 550 EALEISQAQL 560 LYESRRKGQQ 570 PLPAPSSVKT 580 ERKPPPCQGE 590 APEGAGAPSG 600 TEAATGPGGE 610 ARDSSSDSDS 620 SSSEDEDTWK 630 PRSQKRRRGP 640 EAGDDDGFEI 650 VPIEDPARHR 660 ILDPEGLALG 670 AIIASSKKAK 680 RDLIDDSFSR 690 YTFNEDEGEL 700 PEWFVQEEKQ 710 HRIRQLPLDK 720 KEVEYYRKRW 730 REINARPIKK 740 VAEAKARKKR 750 RMLKKLEQTK 760 KKAEAVVNTV 770 DISEREKVAQ 780 LRSLYKKAGL 790 GKEKRQVTYV 800 VAKKGVGRKV 810 RRPAGVRGHF 820 KVVDSRMKKD 830 QRAQQRKEQK KKHKRK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0030687 preribosome, large subunit precursor
Cellular Component GO:0030688 preribosome, small subunit precursor
Molecular Function GO:0016435 rRNA (guanine) methyltransferase activity
Molecular Function GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity
Biological Process GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Process GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Biological Process GO:0031167 rRNA methylation

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.