Search Results
Overview
| Uniprot ID | F1RUL1 |
|---|---|
| Protein Name | Splicing factor 45 |
| Gene Name | RBM17 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 206 | RPRSQSSKAAIPPPV |
| 21 | SKTEGWSKNFKLLQS |
| 24 | EGWSKNFKLLQSQLQ |
| 269 | STALSVEKTSKRGGK |
| 276 | KTSKRGGKIIVGDAT |
| 305 | EILKCPTKVVLLRNM |
| 383 | YFGGRVVKACFYNLD |
| 41 | KAALTQAKSQRTKQS |
| 46 | QAKSQRTKQSTVLAP |
Function
Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites
Protein Sequence
10
MSLYDDLGVE
20
TSDSKTEGWS
30
KNFKLLQSQL
40
QVKKAALTQA
50
KSQRTKQSTV
60
LAPVIDLKRG
70
GSSDERQVVD
80
TPPHVAAGLK
90
DPVPSGFSAG
100
EVLIPLADEY
110
DPMFPNDYEK
120
VVKRQREERQ
130
RQRELERQKE
140
IEEREKRRKD
150
RHEASGFSRR
160
PDPDSDEDED
170
YERERRKRSM
180
GGAAIAPPTS
190
LVEKDKELPR
200
DFPYEEDSRP
210
RSQSSKAAIP
220
PPVYEEQDRP
230
RSPTGPGNSF
240
LANMGGTVAH
250
KIMQKYGFRE
260
GQGLGKHEQG
270
LSTALSVEKT
280
SKRGGKIIVG
290
DATEKDAAKK
300
SDSNPLTEIL
310
KCPTKVVLLR
320
NMVGAGEVDE
330
DLEVETKEEC
340
EKYGKVGKCV
350
IFEIPGAPDD
360
EAVRIFLEFE
370
RVESAIKAVV
380
DLNGRYFGGR
390
VVKACFYNLD
400
KFRVLDLAEQ
V
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000380 | alternative mRNA splicing, via spliceosome |
| Biological Process | GO:0045292 | mRNA cis splicing, via spliceosome |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.