Search Results
Overview
| Uniprot ID | F1RVS8 |
|---|---|
| Protein Name | Mitochondrial carrier homolog 1 |
| Gene Name | MTCH1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 232 | QFVGREAKYSGVLSS |
Function
Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins. May play a role in apoptosis
Protein Sequence
10
MGASDPEVAP
20
WARGGAAGMA
30
GAGAGAGARG
40
GAAAGVEARA
50
RDPPPAHRAH
60
PRHPRPAAQP
70
SARRMDGASG
80
GLGSGDNAPT
90
TEALFVALGA
100
GVTALSHPLL
110
YVKLLIQVGH
120
EPMPPTIGTN
130
VLGRKVLYLP
140
SFFTYAKYIV
150
QVDGKIGLFR
160
GLSPRLMSNA
170
LSTVTRGSMK
180
KVFPPDEIEQ
190
VSNKDDMKTS
200
LKKVVKETSY
210
EMMMQCVSRM
220
LAHPLHVISM
230
RCMVQFVGRE
240
AKYSGVLSSI
250
GKIFKEEGLL
260
GFFVGLIPHL
270
LGDVVFLWGC
280
NLLAHFINAY
290
LVDDSVSDTP
300
GGLGNDQNPG
310
SQFSQALAIR
320
SYTKFVMGIA
330
VSMLTYPFLL
340
VGDLMAVNNC
350
GLQAGLPPYS
360
PVFKSWIHCW
370
KYLSVQGQLF
380
RGSSLLFRRV
SSGSCFALE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016020 | membrane |
| Cellular Component | GO:0005741 | mitochondrial outer membrane |
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0032977 | membrane insertase activity |
| Biological Process | GO:0006915 | apoptotic process |
| Biological Process | GO:0043065 | positive regulation of apoptotic process |
| Biological Process | GO:0045040 | protein insertion into mitochondrial outer membrane |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.