Search Results
Overview
| Uniprot ID | F1RWZ4 |
|---|---|
| Protein Name | Enoyl-CoA delta isomerase 2 |
| Gene Name | ECI2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 380 | MRHQEKEKLHAVNAE |
| 77 | MNQVKLLKEDPGNEV |
| 85 | EDPGNEVKLKLYALY |
| 87 | PGNEVKLKLYALYKQ |
Function
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates
Protein Sequence
10
MMSRLLPAVS
20
GRVPGVPPTP
30
AMARVVGLLA
40
HRWFSGAFRG
50
PLQVIRCPAP
60
QLHVSGPAMA
70
ASQEDFAKAM
80
NQVKLLKEDP
90
GNEVKLKLYA
100
LYKQATEGPC
110
NAPKPGMLDF
120
ILKAKWDAWN
130
ALGNLPKETA
140
RQNYVDLVSS
150
LSASSCSQVT
160
PAADKKQAES
170
DSLVVTSEDG
180
ITTIRLNRPA
190
KKNALTTQMY
200
RDIMRALEAA
210
SEDSSRITVL
220
TGSGDYYCSG
230
NDLSNFKDIP
240
PDKVEERAQS
250
SAVLLRDFVD
260
CFIDFPKPLI
270
AVVNGPAVGI
280
SVTLLGLFDV
290
VYASDRATFH
300
TPFSHLGQSP
310
EGCSSYIFPK
320
MMGPSKAAEM
330
LIFGKKLTAR
340
EALAQGLVTA
350
VFPDDTFQKE
360
VWARLKAYAK
370
LPPNAMRIAK
380
RLMRHQEKEK
390
LHAVNAEESR
400
VLAERWVSDE
410
CITAIVAFLS
KKAKL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005782 | peroxisomal matrix |
| Molecular Function | GO:0004165 | delta(3)-delta(2)-enoyl-CoA isomerase activity |
| Molecular Function | GO:0000062 | fatty-acyl-CoA binding |
| Biological Process | GO:0006635 | fatty acid beta-oxidation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.