Search Results
Overview
| Uniprot ID | F1RX65 |
|---|---|
| Protein Name | Transcription initiation factor IIE subunit beta |
| Gene Name | GTF2E2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 24 | LSTPVVEKRSVSSES |
| 37 | ESSSSSSKKKKAKLE |
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase
Protein Sequence
10
MDPSLLRERE
20
LFRKRALSTP
30
VVEKRSVSSE
40
SSSSSSKKKK
50
AKLEHGGSSS
60
SKQNSDHSNG
70
SFNLKALSGS
80
SGYKFGVLAK
90
IVNYMKTRHQ
100
RGDTHPLTLE
110
EILDETQHLD
120
IGKQKQWLMT
130
EALVNNPKIE
140
VIDGKYAFKP
150
KYNLKDKKAL
160
LRLLDKHDQR
170
GLGGILLEDI
180
EEGLPNSQKA
190
VKALGDQILF
200
VNRPDKKKIL
210
FFNDKSCQFS
220
VDEEFQKLWR
230
SVTVDSMDEE
240
KIEEYLKRQG
250
ISSMQESGPK
260
KVAPIQRRKK
270
PASQKKRRFK
280
THNEHLAGVL
290
KDYSDIAPGK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005669 | transcription factor TFIID complex |
| Cellular Component | GO:0005673 | transcription factor TFIIE complex |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0016251 | RNA polymerase II general transcription initiation factor activity |
| Biological Process | GO:0051123 | RNA polymerase II preinitiation complex assembly |
| Biological Process | GO:0006367 | transcription initiation at RNA polymerase II promoter |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.