Search Results
Overview
| Uniprot ID | F1RXY7 |
|---|---|
| Protein Name | Translin |
| Gene Name | TSN |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 197 | LSIRGFNKETVAACS |
| 54 | KTHLTSLKTKFPAEQ |
| 56 | HLTSLKTKFPAEQYY |
Function
DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots
Protein Sequence
10
EIRKVVQSLE
20
QTAREILTLL
30
QGVHQGAGFQ
40
DIPKRCLKAR
50
EHFGTVKTHL
60
TSLKTKFPAE
70
QYYRFHEHWR
80
FVLQRLVFLA
90
AFVVYLESET
100
LVTREAVTEI
110
LGIEPDREKG
120
FHLDVEDYLS
130
GVLILASELS
140
RLSVNSVTAG
150
DYARPLHIST
160
FINELDSGFR
170
LLNLKNDSLR
180
KRYDGLKYDV
190
KKVEEVVYDL
200
SIRGFNKETV
AACSEK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0004519 | endonuclease activity |
| Molecular Function | GO:0016787 | hydrolase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0043565 | sequence-specific DNA binding |
| Molecular Function | GO:0003697 | single-stranded DNA binding |
| Biological Process | GO:0016070 | RNA metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.