Search Results

Overview

Uniprot IDF1RYU9
Protein NameGeneral vesicular transport factor p115
Gene NameUSO1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
572 SYTKEKLKQLIEKRI
625 HEFTKLVKELEGVIT
633 ELEGVITKAIHKSSE

Function

General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity

Protein Sequence

10 MNFLRGVMGG 20 QSAGPQHTEA 30 ETIQKLCDRV 40 ASSTLLDDRR 50 NAVRALKSLS 60 KKYRLEVGIQ 70 AMEHLIHVLQ 80 TDRSDSEIIG 90 YALDTLYNII 100 SNDEEEEVEE 110 NSTRQSEDLG 120 SQFTEIFIKQ 130 QENVTLLLSL 140 LEEFDFHVRW 150 PGVKLLTSLL 160 KQLGPQVQQI 170 ILVSPMGVSR 180 LMDLLADSRE 190 VIRNDGVLLL 200 QALTRNNGAI 210 QKIVAFENAF 220 ERLLDIITEE 230 GNSDGGIVVE 240 DCLILLQNLL 250 KNNNSNQNFF 260 KEGSYIQRMK 270 PWFEVGDENS 280 GWSAQKVTNL 290 HLMLQLVRVL 300 VSPNNPPGAT 310 SSCQKAMFQC 320 GLLQQLCTIL 330 MATGVPADIL 340 TETINTVSEV 350 IRGCQVNQDY 360 FASVNAPSNP 370 PRPAIVVLLM 380 SMVNERQPFV 390 LRCAVLYCFQ 400 CFLYKNQKGQ 410 GEIVSTLLPS 420 TIDATGISVS 430 AGQLLCGGLF 440 STDSLSNWCA 450 AVALAHALQE 460 NATQKEQLLR 470 VQLATSIGNP 480 PVSLLQQCTN 490 ILSQGDKIDR 500 RGSKIQTRVG 510 LLMLLCTWLS 520 NCPIAVTHFL 530 HNSANVPFLT 540 GQIAENLGEE 550 EQLVQGLCAL 560 LLGISIYFND 570 NSLESYTKEK 580 LKQLIEKRIG 590 KENFIEKLGF 600 ISKHEFYSRA 610 SQKPQPNFPS 620 PEYMIFDHEF 630 TKLVKELEGV 640 ITKAIHKSSE 650 EDKKEEEVKK 660 TLEQHDSIVT 670 HYKNMIREQD 680 LQLEELKQQI 690 STLKCQNEQL 700 QTAVTQQVSQ 710 IQQHKDQYNL 720 LKVQLGKDNQ 730 PQGSYNDGSQ 740 MNGIQPEEIG 750 RLREEIEELK 760 SNQELLQNQL 770 AEKDSLIENL 780 KSSQPSPGAN 790 EESSATDSAR 800 DSEQIADLKQ 810 ELATLKSQLN 820 SQSIEITKLQ 830 TEKQELLQKT 840 EAFAKSVPEP 850 EQSETVTAAK 860 ATDVEGRLSA 870 LLQETKELKN 880 EIKALSEERT 890 AIKEQLDASN 900 STIAILQNEK 910 NKLEVDITDS 920 KKNKTIFWCC 930 WLIRIRKYFH

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005829 cytosol
Cellular Component GO:0005783 endoplasmic reticulum
Cellular Component GO:0012507 ER to Golgi transport vesicle membrane
Cellular Component GO:0000139 Golgi membrane
Cellular Component GO:0005795 Golgi stack
Cellular Component GO:0048471 perinuclear region of cytoplasm
Biological Process GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Biological Process GO:0048211 Golgi vesicle docking
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0061025 membrane fusion
Biological Process GO:0045056 transcytosis
Biological Process GO:0048280 vesicle fusion with Golgi apparatus

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.