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Overview

Uniprot IDF1RZ01
Protein NameChitinase domain-containing protein 1
Gene NameCHID1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
326 ARYIQTLKDHRPRIT
71 HRSYCSAKALRKHFA

Function

Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro)

Protein Sequence

10 MRSLLGALWL 20 ALACGSAHGT 30 LSKSDAKKAA 40 SKTLPEKTQV 50 AGVPVQERGL 60 VVTDLRAEDV 70 VLEHRSYCSA 80 KALRKHFAGD 90 VLGYVTPWNS 100 HGYDIAKIFA 110 GKFTHVAPVW 120 LQLRRHGREM 130 FEVTGLDDVD 140 QGWMRAVRKQ 150 TKGLRIVPRL 160 RFEDWTYEDF 170 RNVLDSEDEI 180 EELSRTVVQV 190 AKSQRFDGFV 200 VEVWNQLLIQ 210 KHVGLIHMLT 220 HVVEALHQAR 230 LLAILVIPPA 240 VAPGTNKLGV 250 FTHKEFEQLA 260 PLLDGFSLMT 270 YDYSTAQQPG 280 PNAPLSWVRA 290 CVQVLDPKSR 300 WRSKILLGLN 310 FYGMDYAASK 320 DAREPIIGAR 330 YIQTLKDHRP 340 RITWDSQAAE 350 HVFEYKKNRG 360 GRHIVFYPTL 370 KSLQVRLELA 380 RELGVGLSIW 390 ELGQGLDYFY DLL

Gene Ontology

Classification GO ID Description
Cellular Component GO:0012505 endomembrane system
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0005764 lysosome
Molecular Function GO:0008061 chitin binding
Molecular Function GO:0070492 oligosaccharide binding
Biological Process GO:0005975 carbohydrate metabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.