Search Results
Overview
| Uniprot ID | F1RZT9 |
|---|---|
| Protein Name | Methyl-CpG-binding protein 2 |
| Gene Name | MECP2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 208 | ASEGVQVKRVLEKSP |
| 254 | KRPGRKRKAEADPQA |
| 282 | AAAAAEAKKKAVKES |
| 329 | LVSTLGEKSGKGLKT |
| 406 | LESDGCPKEPAKTQP |
Function
No function data available.
Protein Sequence
10
RCAGLLGAGE
20
EKSEEQDLQG
30
LKDKPLKFKK
40
VKKDKKDDRE
50
GKHEPLQPPA
60
HHSPAEAGKA
70
ETSEGSGSAP
80
AVPEASASPK
90
QRRSIIRDRG
100
PMYDDPTLPE
110
GWTRKLKQRK
120
SGRSAGKYDV
130
YLINPQGKAF
140
RSKVELIAYF
150
EKVGDTSLDP
160
NDFDFTVTGR
170
GSPSRREQKP
180
PKKPKSPKAP
190
GTGRGRGRPK
200
GSGTTRPKAA
210
ASEGVQVKRV
220
LEKSPGKLLV
230
KMPFQASPGS
240
KAEGGGATTS
250
AQVMVIKRPG
260
RKRKAEADPQ
270
AIPKKRGRKP
280
GSVVAAAAAE
290
AKKKAVKESS
300
IRSVQETVLP
310
IKKRKTRETV
320
SIEVKEVVKP
330
LLVSTLGEKS
340
GKGLKTCKSP
350
GRKSKEGSAS
360
SPPKKEHHHH
370
HHHAEPPKAP
380
APLLPPPPPP
390
PPEPHNVCRE
400
EKMPRAGSLE
410
SDGCPKEPAK
420
TQPAVATAAT
430
AAEKYKHRGE
440
GERKDIVSSS
450
MPRPNREEPV
460
DSRTPVTERV
S
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0000792 | heterochromatin |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0003682 | chromatin binding |
| Molecular Function | GO:0010385 | double-stranded methylated DNA binding |
| Molecular Function | GO:0140566 | histone reader activity |
| Molecular Function | GO:0008327 | methyl-CpG binding |
| Molecular Function | GO:0140693 | molecular condensate scaffold activity |
| Molecular Function | GO:0003729 | mRNA binding |
| Molecular Function | GO:1990841 | promoter-specific chromatin binding |
| Molecular Function | GO:0035197 | siRNA binding |
| Molecular Function | GO:0003714 | transcription corepressor activity |
| Biological Process | GO:0008306 | associative learning |
| Biological Process | GO:0048468 | cell development |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0016525 | negative regulation of angiogenesis |
| Biological Process | GO:0043537 | negative regulation of blood vessel endothelial cell migration |
| Biological Process | GO:0044027 | negative regulation of gene expression via chromosomal CpG island methylation |
| Biological Process | GO:0051151 | negative regulation of smooth muscle cell differentiation |
| Biological Process | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| Biological Process | GO:0030182 | neuron differentiation |
| Biological Process | GO:0007219 | Notch signaling pathway |
| Biological Process | GO:0090063 | positive regulation of microtubule nucleation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.