Search Results
Overview
| Uniprot ID | F1S192 |
|---|---|
| Protein Name | Prefoldin subunit 2 |
| Gene Name | PFDN2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 18 | SSGSGAGKGAVSAEQ |
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins
Protein Sequence
10
MAESSSRAGK
20
SSGSGAGKGA
30
VSAEQVIAGF
40
NRLRQEQRGL
50
ASKAAELEME
60
LNEHSLVIDT
70
LKEVDETRKC
80
YRMVGGVLVE
90
RTVKEVLPAL
100
ENNKEQIQKI
110
IETLTQQLQA
120
KGKELNEFRE
130
KHNIRLMGED
140
EKPTSKENSE
150
GAGAKASSAG
VLVS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0016272 | prefoldin complex |
| Molecular Function | GO:0001540 | amyloid-beta binding |
| Molecular Function | GO:0044183 | protein folding chaperone |
| Molecular Function | GO:0051082 | unfolded protein binding |
| Biological Process | GO:1905907 | negative regulation of amyloid fibril formation |
| Biological Process | GO:0051495 | positive regulation of cytoskeleton organization |
| Biological Process | GO:0006457 | protein folding |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.