Search Results
Overview
| Uniprot ID | F1S369 |
|---|---|
| Protein Name | Target of EGR1 protein 1 |
| Gene Name | TOE1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 346 | RRRGKRLKALLSLPA |
| 474 | WLPECHNKVYLSGKA |
Function
Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing
Protein Sequence
10
MAADSDDGAA
20
SAPAVSDGGV
30
HQSTKSGEEL
40
AIQVPVVDVQ
50
NDNFKEMWPS
60
LLLAIKTASF
70
VAVDTELSGL
80
GDRKSLLNQC
90
IEERYKAVCH
100
AARTRSILSL
110
GLACFKHQPD
120
KGDHSYLVQV
130
FNLTLLCMEE
140
YVIEPKSVQF
150
LVQHGFNFNR
160
QYAQGIPYHK
170
GNDKGDESQS
180
QSVRTLFLEL
190
IRARRPLVLH
200
NGLIDLVFLY
210
QHFYAHLPES
220
LGTFTADLCE
230
MFPAGIYDTK
240
YAAEFHARFV
250
ASYLEYAFRK
260
CERENGKQRA
270
AGSPHLTLEF
280
CSYPSSMRAH
290
IDYRCCMPAT
300
SRPHSTSICD
310
NFSAYGWCPL
320
GPRCPRSHDI
330
DLIIDTDEAV
340
VEDKRRRRRR
350
RGKRLKALLS
360
LPARQTPGET
370
EGGPPAKQVR
380
GEGLKPEEGE
390
PEVAEDETGN
400
QPGSEQGHEN
410
DLDVELEATR
420
PAPADVTAPE
430
APGSQASPNP
440
VPGDGLHRAG
450
FDAFMTGYVM
460
AYVGVGQGLQ
470
PCRSGPWLPE
480
CHNKVYLSGK
490
AVPLTVAKSQ
500
FSRSSKAHNQ
KMKLAWGSG
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0015030 | Cajal body |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016607 | nuclear speck |
| Cellular Component | GO:0005730 | nucleolus |
| Molecular Function | GO:0000175 | 3'-5'-RNA exonuclease activity |
| Molecular Function | GO:0004535 | poly(A)-specific ribonuclease activity |
| Molecular Function | GO:0017069 | snRNA binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0034472 | snRNA 3'-end processing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.