Search Results

Overview

Uniprot IDF1S412
Protein NameCysteine-rich motor neuron 1 protein
Gene NameCRIM1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
532 QCRPRPKKCRPIICD
550 PFGYLKNKHGCDICR
560 CDICRCKKCPELPCS
810 IEDTIPKKVLCHFSG
818 VLCHFSGKAYADEER

Function

May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface

Protein Sequence

10 MYLVAGGRGL 20 AGSLLGLLLL 30 LARSGTRALV 40 CLPCDESKCE 50 EPRSCPGSIV 60 QGVCGCCYMC 70 ARQRNESCGG 80 AYGLHGACDR 90 GLRCVIRPPL 100 NGDSITEYEV 110 GVCEDENWDD 120 DQLLGFEPCN 130 ENLVSGCNII 140 NGKCECDTIR 150 TCNNPFEFPR 160 KDMCLSALKR 170 IEEEKPDCSK 180 ARCEVQFSPR 190 CPEDSVLIEG 200 YAPPGECCPL 210 PSRCVCDPAG 220 CLRKVCQPGY 230 LNILVSKASG 240 KPGECCDLYE 250 CKPVFSVDCS 260 TVECPSVQQA 270 VCPLDSYETQ 280 VRLTADGCCT 290 LPTRCECLSG 300 LCGFPVCEVG 310 STPRIVSRGD 320 GTPGKCCDVF 330 ECVNETKPAC 340 VFNNVEYSDG 350 DMFRMDNCRF 360 CRCQGGVSIC 370 FTAQCGELNC 380 ERYYVPEGEC 390 CPVCEDPVYP 400 FNNPAGCYAN 410 GQIRAHGDRW 420 REDDCTFCQC 430 INGEPHCVAT 440 ACGQSCMNPV 450 KVPGECCPVC 460 EEPTYITIDP 470 PACGELSNCT 480 LTEKDCIYGF 490 KLDHNGCRTC 500 QCKNREELCT 510 GLKRGCTLDC 520 PFGFLTDAHN 530 CEICQCRPRP 540 KKCRPIICDK 550 YCPFGYLKNK 560 HGCDICRCKK 570 CPELPCSKIC 580 PLGFQQDSHG 590 CLICKCREVP 600 ASAGPPILSG 610 TCLSMDGHHH 620 KNEESWHDGC 630 RECYCHNGRE 640 MCALITCPVP 650 ACGNPTIHPG 660 QCCPSCSDDF 670 VVQKPELSTP 680 SICHAPGGEY 690 FVEGETWHID 700 SCTQCTCHSG 710 RVLCETEVCP 720 PLLCQNPTRT 730 QDSCCPQCPD 740 EPLQPSSSHN 750 DSVPSYCKND 760 EGDIFLAAES 770 WKPDVCTSCV 780 CLDSVISCFS 790 ESCPSVSCER 800 PVLRKGQCCP 810 YCIEDTIPKK 820 VLCHFSGKAY 830 ADEERWDIDS 840 CTHCYCLQGQ 850 TLCSTVSCPP 860 LPCVEPINVE 870 GSCCPMCPEM 880 YVPEPTNIPI 890 EKTNHRGEID 900 LEVPLWPTPS 910 ENDIIHLPKD 920 MGHLQVDYRD 930 NNRLHSGEDS 940 SLDSIASVVV 950 PIIIGLSIII 960 AFLFINQKKQ 970 WIPLLCWYRT 980 PTKPSSLNNH 990 LVSVDCKKGA 1000 RVQVDSSQRM 1010 LRIAEPDARL 1020 SGFYSMQRQN 1030 HLQADNFYQT V

Gene Ontology

Classification GO ID Description
Molecular Function GO:0030165 PDZ domain binding
Cellular Component GO:0005576 extracellular region
Cellular Component GO:0016020 membrane
Molecular Function GO:0004867 serine-type endopeptidase inhibitor activity

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.