Search Results
Overview
| Uniprot ID | F1S7D9 |
|---|---|
| Protein Name | Probable ATP-dependent RNA helicase DDX49 |
| Gene Name | DDX49 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 229 | RYLLVPEKVKDAYLV |
Function
ATP-dependent RNA helicase that plays a role in various aspects of RNA metabolism including the regulation of mRNA export and the levels of pre-ribosomal RNA. Regulates the stability and synthesis of pre-ribosomal RNA and thereby regulates cell proliferation. Also possesses antiviral activity by recognizing gammaherpesvirus transcripts in the context of lytic reactivation
Protein Sequence
10
MAGFAELGLS
20
SWLVEQCRQL
30
GLKQPTPVQL
40
GCIPAILEGR
50
DCLGCAKTGS
60
GKTAAFVLPI
70
LQKLSEDPYG
80
IFCLVLTPTR
90
ELAYQIAEQF
100
RVLGKPLGLK
110
DCIIVGGMDM
120
VAQALELSRK
130
PHVVIATPGR
140
LADHLRSSNT
150
FSIKKIRFLV
160
MDEADRLLEQ
170
GCTDFTVDLE
180
AILAAVPARR
190
QTLLFSATLT
200
DTLRELQSLA
210
TNQPFFWEAQ
220
APVRTVEQLD
230
QRYLLVPEKV
240
KDAYLVHLIQ
250
NFQDEHEDWS
260
IIIFTNTCKT
270
CQILCMMLRK
280
FNFPTVALHS
290
MMKQKERFAA
300
LAKFKSSIYR
310
ILIATDVASR
320
GLDIPTVQVV
330
INHNTPGLPK
340
IYIHRVGRTA
350
RAGRQGQAIT
360
LVTQYDIHLV
370
HAIEEQIKKK
380
LEEFSVEEAE
390
VLQILTQVNV
400
VRRECEIKLE
410
AANFDEKKEI
420
NKRKQMILEG
430
KDPDLEAKRK
440
AELAKIKQKN
450
RRFKEKVEQA
460
LQRQKAGRAG
470
HGGCPPRAQP
480
RAHSSPAPSQ
GPA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0005524 | ATP binding |
| Molecular Function | GO:0016787 | hydrolase activity |
| Molecular Function | GO:0003723 | RNA binding |
| Molecular Function | GO:0003724 | RNA helicase activity |
| Biological Process | GO:0030307 | positive regulation of cell growth |
| Biological Process | GO:0044357 | regulation of rRNA stability |
| Biological Process | GO:0006364 | rRNA processing |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.