Search Results
Overview
| Uniprot ID | F1S8H0 |
|---|---|
| Protein Name | U6 snRNA-associated Sm-like protein LSm7 |
| Gene Name | LSM7 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 20 | DLSKYIDKTIRVKFQ |
| 25 | IDKTIRVKFQGGREA |
Function
Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA
Protein Sequence
10
MFPKKKKKES
20
ILDLSKYIDK
30
TIRVKFQGGR
40
EASGILKGFD
50
PLLNLVLDGT
60
IEYMRDPDDQ
70
YKLTEDTRQL
80
GLVVCRGTSV
90
VLICPQDGME
100
AIPNPFIQQQ
DA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005681 | spliceosomal complex |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0000398 | mRNA splicing, via spliceosome |
| Biological Process | GO:0000956 | nuclear-transcribed mRNA catabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.