Search Results

Overview

Uniprot IDF1S9G9
Protein NameBRO1 domain-containing protein BROX
Gene NameBROX
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
156 KEVHRSLKIAAGIFK

Function

Nuclear envelope-associated factor that is involved in the nuclear envelope ruptures during interphase (NERDI) repair, where it is locally recruited by CHMP5 and reduces cytoskeletal stress through its action on SYN2 to help reseal the ruptured membrane

Protein Sequence

10 MLQKHLEKMT 20 HWFHRNPLKA 30 TAPVSFNYYG 40 VITGPAASKI 50 CSDLRSSRAR 60 LLELFTDLSC 70 NPEMMKSAAD 80 SYFSLLQGFI 90 NSLDESTQES 100 KLRYIQNFKW 110 TDTLQGQVPS 120 AQQDAVFELI 130 SMGFNVALWY 140 TKYASRLAGK 150 ENITEDEAKE 160 VHRSLKIAAG 170 IFKHLKESHI 180 AKLITPAEKG 190 RDLEARLLEA 200 YIIQCQAEAQ 210 EVTIARAIEL 220 KHAPGLIAAL 230 AYETANFYQK 240 ADHTLSSLEP 250 AYSAKWRKYL 260 HLKMCFYTAY 270 AYCYHGQTLL 280 ASDKCGEAIR 290 SLQEAEKFYA 300 KAEALCKEYG 310 ETKGPGPTVK 320 PSGHLFFRKL 330 GTLVKNTLEK 340 CQRENGFIYF 350 QKVPTEAPQL 360 ELKANYGLVE 370 PVPFEFPPLS 380 SHWTPEAMAA 390 FDLTQRPKDD 400 RGKPKPEEVV 410 KPVKEPDIKP QKDTGCSVS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0031965 nuclear membrane
Biological Process GO:0007084 mitotic nuclear membrane reassembly

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.