Search Results

Overview

Uniprot ID	F1S9S9
Protein Name	Far upstream element-binding protein 1
Gene Name	FUBP1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
153	IQQESGCKIQIAPDS
263	RITGDPYKVQQAKEM
414	KTGLIIGKGGETIKS

Function

Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription

Protein Sequence

10 MADYSTVPPP 20 SSGSAGGGGG 30 GGGGGGVNDA 40 FKDALQRARQ 50 IAAKIGGDAG 60 TSLNSNDYGY 70 GGQKRPLEDG 80 DGSWTSPSST 90 THWEGMPSPF 100 KDQPDAKKVA 110 PQNDSFGTQL 120 PPMHQQQRSV 130 MTEEYKVPDG 140 MVGFIIGRGG 150 EQISRIQQES 160 GCKIQIAPDS 170 GGLPERSCML 180 TGTPESVQSA 190 KRLLDQIVEK 200 GRPAPGFHHG 210 DGPGNAVQEI 220 MIPASKAGLV 230 IGKGGETIKQ 240 LQERAGVKMV 250 MIQDGPQNTG 260 ADKPLRITGD 270 PYKVQQAKEM 280 VLELIRDQGG 290 FREVRNEYGS 300 RIGGNEGIDV 310 PIPRFAVGIV 320 IGRNGEMIKK 330 IQNDAGVRIQ 340 FKPDDGTTPD 350 RIAQITGPPD 360 RCQHAAEIIT 370 DLLRSVQAGN 380 PGGPGPGGRG 390 RGRGQGNWNM 400 GPPGGLQEFN 410 FIVPTGKTGL 420 IIGKGGETIK 430 SISQQSGARI 440 ELQRNPPPNA 450 DPNMKLFTIR 460 GTPQQIDYAR 470 QLIEEKIGGP 480 VNPLGPPVPH 490 GPHGVPGPHG 500 PPGPPGPGTP 510 MGPYNPAPYN 520 PGPPGPAPHG 530 PPAPYAPQGW 540 GNAYPHWQQQ 550 APPDPAKTGT 560 DPNSAAWAAY 570 YAHYYQQQAQ 580 PPPAAPAGAP 590 TTTQTNGQGD 600 QQNPAPAGQV 610 DYTKAWEEYY 620 KKMGQAVPAP 630 TGAPPGGQPD 640 YSAAWAEYYR 650 QQAAYYAQTS 660 PQGMPQHPPA PQGQ

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Cellular Component	GO:0005654	nucleoplasm
Cellular Component	GO:0005634	nucleus
Molecular Function	GO:0003677	DNA binding
Molecular Function	GO:0003730	mRNA 3'-UTR binding
Biological Process	GO:0006351	DNA-templated transcription
Biological Process	GO:0010628	positive regulation of gene expression
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.