Search Results

Overview

Uniprot ID	F1SAY9
Protein Name	WD repeat-containing protein 3
Gene Name	WDR3
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
161	QALFLREKNLLVSSG
185	LDTQHCFKTVVGHRT
360	IQRVTNIKTSAKIKS
887	LKETTISKVSQVRDV

Function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 MGLTKQYLRY 20 VASAVFGLIG 30 SQKGNIVFVT 40 LRGEKGRYVA 50 VPACEHVFIW 60 DLRKGEKILI 70 LQGLKHEVTC 80 LCPSPDGLHL 90 AVGYEDGSIR 100 IFSLLSGEGN 110 VTFNGHKAAV 120 TSLKYDQLGG 130 RLASGSKDTD 140 IIVWDVINES 150 GLYRLKGHKD 160 AITQALFLRE 170 KNLLVSSGKD 180 TMVKWWDLDT 190 QHCFKTVVGH 200 RTEVWGLVLV 210 SEEKRLITGA 220 SDSELRAWDI 230 AYLEEIEDPE 240 EPEPKKIKGS 250 SPRMQDTDET 260 EDGTLEMDEA 270 PEDRILTCRK 280 AGSIMREGRD 290 RVVNLAVDRT 300 GRILACHGTD 310 SVLEVFRVLS 320 IEEIQKKMDK 330 KLKKARKKAK 340 LNSGKEEEED 350 LEVSVEMTLQ 360 DEIQRVTNIK 370 TSAKIKSFDL 380 IHSPQGELKA 390 VFLLQNNLVE 400 LYSLNPSVPA 410 SQPVRTSRIT 420 IGGHRSDVRT 430 LSFSSDNIAV 440 LSGAAESIKI 450 WNRSTLQCIR 460 TMTCEYALCS 470 FFVPGDRQVV 480 IGTKTGKLQL 490 YDLASGNLLE 500 TVDAHDGALW 510 SLSLSPDQRG 520 FVTGGADKSV 530 KFWDFELVKD 540 ENSTQKRLSV 550 KQTRTLQLDE 560 EVLCVSYSPN 570 QKLLAVSLLD 580 CTVKIFYVDT 590 LKFFLSLYGH 600 KLPVICMDIS 610 YDGALIATGS 620 ADRNVKIWGL 630 DFGDCHKSLF 640 AHDDSVMYLK 650 FVPKSHLFFT 660 AGKDRKIKQW 670 DADKFEHVQT 680 LEGHHQEIWC 690 LAISPSGDYV 700 VSSSHDKSLR 710 LWERTREPLI 720 LEEEREMQRE 730 AEYEESVAKE 740 DQPAVPGETQ 750 GDNYFTGKKT 760 IETIKAAERI 770 MEAIELYREE 780 TAKMREHKAI 790 CKAAGKEVPL 800 PINPILMAYG 810 NISPSAYVLE 820 IFKGIKSSEL 830 EESLLVLPFS 840 YVPDILKLFN 850 EFIQLGSDIE 860 LLCRCLFFLL 870 RIHFGQITSN 880 QMLVPVIEKL 890 KETTISKVSQ 900 VRDVIGFNMA 910 GLDFLKRECE 920 ARSEVMFFAD 930 ATSHLEEKKR 940 KRKKREKLIL TFT

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005654	nucleoplasm
Cellular Component	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome
Cellular Component	GO:0032040	small-subunit processome
Molecular Function	GO:0030515	snoRNA binding
Biological Process	GO:0030490	maturation of SSU-rRNA

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.