Search Results
Overview
| Uniprot ID | F1SB14 |
|---|---|
| Protein Name | Mediator of RNA polymerase II transcription subunit 9 |
| Gene Name | MED9 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 133 | TKSQLLQKYKSLCMF |
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
Protein Sequence
10
MASVGVPAGR
20
QAEDALPPPT
30
EPPMPETKPL
40
PTPQLPTPVS
50
APQPQPAPRP
60
PSPAVVKAEE
70
NCSFLPLVHN
80
VIKCMDKDGP
90
DVHQDLNALK
100
TKFQEMRKAV
110
SAMPGIHLSP
120
EQQQQQLLSL
130
REQVRTKSQL
140
LQKYKSLCMF
EIPKE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0016592 | mediator complex |
| Molecular Function | GO:0003712 | transcription coregulator activity |
| Biological Process | GO:0006351 | DNA-templated transcription |
| Biological Process | GO:0006357 | regulation of transcription by RNA polymerase II |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.