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Overview

Uniprot IDF1SBH2
Protein NameProtein transport protein SEC23
Gene NameSEC23B
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
193 SYVFRGTKDLTAKQI
320 RSWHDIEKDNARFMK
564 QKFGQYNKEDPTSFR

Function

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex

Protein Sequence

10 MATYLEFIQQ 20 NEERDGVRFS 30 WNVWPSSRLE 40 ATRMVVPLAC 50 LLTPLKERPD 60 LPPVQYEPVL 70 CSRPTCKAIL 80 NPLCQVDYRA 90 KLWACNFCFQ 100 RNQFPPAYAG 110 ISEVNQPAEL 120 MPQFSTIEYV 130 IQRGAQSPLI 140 FLYVVDTCLE 150 EDDLQALKES 160 LQMSLSLLPP 170 DALVGLITFG 180 RMVQVHELSC 190 EGISKSYVFR 200 GTKDLTAKQI 210 QDMLGLTKPA 220 MPMQPARPAQ 230 PQDQPFISSR 240 FLQPVHKIDM 250 NLTDLLGELQ 260 RDPWPVTQGK 270 RPLRSTGVAL 280 SIAVGLLEGT 290 FPNTGARIML 300 FTGGPPTQGP 310 GMVVGDELKV 320 PIRSWHDIEK 330 DNARFMKKAT 340 KHYEMLANRT 350 AANGHCIDIY 360 ACALDQTGLL 370 EMKCCTNLTG 380 GHMVMGDSFN 390 TSLFKQTFQR 400 IFSKDFNGNF 410 RMAFGATLEV 420 KTSRELKIAG 430 AIGPCVSLNM 440 RGPCVSENEL 450 GVGGTSQWKI 460 CGLDPTSTLG 470 IYFEVVNQHN 480 APVPQGGRGA 490 IQFVTHYQHS 500 STQRRIRVTT 510 IARNWADAQS 520 QLKHIEAAFD 530 QEAAAVLMAR 540 LGVFRTESEE 550 GPDVLRWLDR 560 QLIRLCQKFG 570 QYNKEDPTSF 580 RLSDSFSLYP 590 QFMFHLRRSP 600 FLQVFNNSPD 610 ESSYYRHHFA 620 RQDLTQSLIM 630 IQPILYSYSF 640 HGPPEPVLLD 650 SSSILADRIL 660 LMDTFFQIVI 670 YLGETIAQWR 680 KAGYQDMPEY 690 ENFKHLLQAP 700 LDDAQEILQA 710 RFPMPRYINT 720 EHGGSQARFL 730 LSKVNPSQTH 740 NNLYAWGQET 750 GAPILTDDVS 760 LQVFMDHLKK LAVSSAC

Gene Ontology

Classification GO ID Description
Cellular Component GO:0030127 COPII vesicle coat
Cellular Component GO:0005829 cytosol
Cellular Component GO:0070971 endoplasmic reticulum exit site
Cellular Component GO:0005789 endoplasmic reticulum membrane
Cellular Component GO:0048471 perinuclear region of cytoplasm
Molecular Function GO:0005096 GTPase activator activity
Molecular Function GO:0008270 zinc ion binding
Biological Process GO:0090110 COPII-coated vesicle cargo loading
Biological Process GO:0006886 intracellular protein transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.