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Overview

Uniprot IDF1SC81
Protein NameCentrosomal protein of 55 kDa
Gene NameCEP55
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
145 RLAELEGKASTLRLS

Function

Plays a role in mitotic exit and cytokinesis. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. Required for successful completion of cytokinesis. Not required for microtubule nucleation. Plays a role in the development of the brain and kidney

Protein Sequence

10 MSSRSPKELI 20 KSKWGSKPSN 30 SKSETALERF 40 RGEIAALKTS 50 VDEITSGKGK 60 LTDKDRHRLL 70 EKIRVLEAER 80 EKNAYCLTEK 90 DKEIQRLRDQ 100 LKAKYSTTAL 110 LEQLEEKTKE 120 GERREQLLKS 130 LSEETDVLKK 140 QLSATTARLA 150 ELEGKASTLR 160 LSQTVATSCL 170 NPSMSEIHEM 180 EVQLKDALEK 190 NQQWLVYDQQ 200 REVYVKGLLA 210 KIFELEQQKS 220 ETAAHVLPQQ 230 TKKTESEGYL 240 QEEKQKYYNH 250 LLVNAKKDLE 260 VERQTVTQLN 270 FELSEFRRKY 280 EETQKEVQDL 290 NQLLCLQRKA 300 DVQHLEDDRH 310 KTEKIQRLKE 320 ENDLAREKLG 330 EEKKRSEELL 340 SQVQFLYTSL 350 LKQQEEQTKV 360 ALLEQQIQAC 370 TLDFENEKLD 380 RQNMQHQLHV 390 ILKELRKARN 400 QITQLESLKQ 410 FREFAFTEPL 420 VTFQGETENR 430 GKVASPKSPT 440 AALNESLVEC 450 PKCNIQYPAT 460 EHRDLLVHVE YCSK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005814 centriole
Cellular Component GO:0005813 centrosome
Cellular Component GO:0032154 cleavage furrow
Cellular Component GO:0005829 cytosol
Cellular Component GO:0090543 Flemming body
Cellular Component GO:0045171 intercellular bridge
Cellular Component GO:0030496 midbody
Molecular Function GO:0042802 identical protein binding
Biological Process GO:1904888 cranial skeletal system development
Biological Process GO:0045184 establishment of protein localization
Biological Process GO:0061952 midbody abscission
Biological Process GO:0000281 mitotic cytokinesis
Biological Process GO:0051896 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.