Search Results

Overview

Uniprot IDF1SCS4
Protein NameStructural maintenance of chromosomes protein 6
Gene NameSMC6
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
5 ***MAKRKEGNFFSP

Function

No function data available.

Protein Sequence

10 MAKRKEGNFF 20 SPENAKRPRQ 30 EELDDFDKDG 40 DEDECTVSFT 50 NGTSTLTAAE 60 VGIIESIQLK 70 NFMCHSMLGP 80 FKFGSNVNFV 90 VGNNGSGKSA 100 VLTALIVGLG 110 GKAIATNRGS 120 SLKGFVKDGQ 130 NSADISITLR 140 NRGDDAYRAN 150 VYGDSIIVQQ 160 HISMDGSRSY 170 KLRSQTGAVV 180 STKKEELIGI 190 LDHFNIQVDN 200 PVSVLTQEMS 210 KQFLQSKNEG 220 DKYKFFMKAT 230 QLEQMKEDYS 240 YIMETKERTK 250 EQINQGEERL 260 TELKRQCLEK 270 EERFQSIAGL 280 STMKTNLEDL 290 KHEMAWAVVN 300 EIEKQLNAIR 310 DNIKIGEDRA 320 ARLERKTEEQ 330 QVRLNEAEKK 340 YKDIQDKLEK 350 ISQETNARAP 360 ECLALKADLT 370 SKKRVYNEAE 380 VLYNRSLNEY 390 RALKKDDEQL 400 CKRIEELRKS 410 ADQSMEPERL 420 ERQKKISWLK 430 ERVKALQDQE 440 ISVNQEIEQF 450 QQAVEKDKEE 460 HTRIKREELD 470 VKQILNYNQK 480 QLKELKDSKT 490 DRLKRFGPNV 500 PALLEAIDNA 510 YRRGQFTYKP 520 VGPLGACIRL 530 RDPELALAIE 540 SCLKGLLQAY 550 CCHNHADERV 560 LQALMKRFYS 570 PGTSRPQIIV 580 SEFRNEVYDV 590 RHRAAYHPEF 600 PTVLTALEID 610 NAVVANSLID 620 MRGIETVLLI 630 KNNSVARAVM 640 QSPKPPKNCR 650 EAFTADGDQV 660 FAGRYYSSEN 670 TRPKFLSRDV 680 DSEISDLENE 690 VENKKAQILN 700 LQQHLCALEK 710 DIKRNEEFLR 720 RCQLHYKELK 730 MKIRKCLSEI 740 RELENIEEHQ 750 SVDIATLEDE 760 AHENKMKMKT 770 VEKNMEKQKE 780 HMEYLKSLKI 790 EAENKYDAIK 800 LKINQLSEQA 810 DPLKDELNLA 820 DSEVDNQKRG 830 KRHYEDKQKE 840 HLDTLNKKKR 850 ELDMKEKELE 860 EKMSQARQIC 870 PERIEVKKSA 880 SILDKEINRL 890 RQKIQAEHAS 900 HGDREEIMRQ 910 YQEAKETYLD 920 LDNKVRTLKR 930 FIKLLEEIMT 940 HRYKTYQQFR 950 RCLTLRCKLY 960 FDNLLSQRAY 970 CGKMNFDHKN 980 ETLTISVQPG 990 EGSKAAFNDM 1000 RSLSGGERSF 1010 STVCFILSLW 1020 SIAESPFRCL 1030 DEFDVYMDMV 1040 NRRIAMDMIL 1050 KMADSQRFRQ 1060 FILLTPQSMS 1070 SLPPSKLIRI 1080 LRMSDPERGQ 1090 TTLPFRPVSQ EEEEDRS

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000775 chromosome, centromeric region
Cellular Component GO:0000781 chromosome, telomeric region
Cellular Component GO:0035061 interchromatin granule
Cellular Component GO:0097431 mitotic spindle pole
Cellular Component GO:0016607 nuclear speck
Cellular Component GO:0005634 nucleus
Cellular Component GO:0016605 PML body
Cellular Component GO:0000803 sex chromosome
Cellular Component GO:0035861 site of double-strand break
Cellular Component GO:0030915 Smc5-Smc6 complex
Molecular Function GO:0005524 ATP binding
Molecular Function GO:0016887 ATP hydrolysis activity
Molecular Function GO:0003684 damaged DNA binding
Molecular Function GO:0000217 DNA secondary structure binding
Molecular Function GO:0003697 single-stranded DNA binding
Molecular Function GO:0031625 ubiquitin protein ligase binding
Biological Process GO:0090398 cellular senescence
Biological Process GO:0000724 double-strand break repair via homologous recombination
Biological Process GO:0044828 host-mediated suppression of viral genome replication
Biological Process GO:0051984 positive regulation of chromosome segregation
Biological Process GO:0000722 telomere maintenance via recombination

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.