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Overview

Uniprot ID	F1SDP3
Protein Name	Ornithine aminotransferase
Gene Name	OAT
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
102	PKIVNALKRQVDKLT
386	AIVIRETKDYDAWKV
392	TKDYDAWKVCLRLRD
66	PVALERGKGVYVWDV

Function

Catalyzes the reversible interconversion of L-ornithine and 2-oxoglutarate to L-glutamate semialdehyde and L-glutamate

Protein Sequence

10 MFSKLAHLQT 20 VTLLRRGVHS 30 TVASATSVAT 40 KRTIQGPPSS 50 DYIFEREAKY 60 GAHNYHPLPV 70 ALERGKGVYV 80 WDVEGRRYFD 90 FLSAYSAVNQ 100 GHCHPKIVNA 110 LKRQVDKLTL 120 TSRAFYNDVL 130 GEYEEYITKL 140 FNYHKVLPMN 150 TGVEAGETAC 160 KIARRWGYTV 170 KGIPKYKAKI 180 IFAAGNFWGR 190 TLSAISSSTD 200 PTSYDGFGPF 210 MPGFEIIPYS 220 DLPALERALQ 230 DPNVAAFMVE 240 PIQGEAGVVV 250 PDPGYLVGVR 260 ELCTQHQVLF 270 IADEIQTGLA 280 RTGRWLAVDH 290 ENVRPDIILL 300 GKALSGGLYP 310 VSAVLCDDEI 320 MLTIKPGEHG 330 STYGGNPLGC 340 RVAIAALEVL 350 EEENLAENAE 360 KMGTILRNEL 370 MKLPSDIVTT 380 VRGKGLLNAI 390 VIRETKDYDA 400 WKVCLRLRDN 410 GLLAKPTHGD 420 IIRFAPPLVI 430 KEDEILESVE IINKTVLSF

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0005737	cytoplasm
Molecular Function	GO:0042802	identical protein binding
Molecular Function	GO:0004587	ornithine aminotransferase activity
Molecular Function	GO:0030170	pyridoxal phosphate binding
Biological Process	GO:0019544	L-arginine catabolic process to L-glutamate
Biological Process	GO:0010121	L-arginine catabolic process to proline via ornithine
Biological Process	GO:0055129	L-proline biosynthetic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.