Search Results

Overview

Uniprot IDF1SE91
Protein NameNucleolar protein 6
Gene NameNOL6
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
38 GKRDSSKKRPVAGSP
787 ATHTDVLKDGFVFRI

Function

Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome

Protein Sequence

10 MGPAPAGAQH 20 RGTAEEPEMM 30 ESALEGPVKE 40 GKRDSSKKRP 50 VAGSPVGLLQ 60 PVKLSRAELY 70 KEPTNEELNR 80 LRETESLFHS 90 SLLRLQVEEL 100 LKEVRLSEKK 110 KERIDAFLRE 120 VNQRIMRVPP 130 TSETELTDQS 140 WLPDGVRVPL 150 HQVPYTVKGC 160 FRFLAPAQVT 170 VVGSYLLGTC 180 IRPDINVDMA 190 LTMPREILQD 200 KDGLNQRYFR 210 KRALYLAHLA 220 HHLAQDPLFG 230 SVHFSYTSGC 240 HLKPSLLLRP 250 HGKDKHLVTV 260 RLHPCPPREF 270 FRLCRLLPSK 280 NNVRSAWYRG 290 QSLSGDGSPE 300 PPTPHYNTWV 310 LQDTALESHM 320 QLLSTMLGTA 330 SGLKDGVALL 340 KVWLRQRELD 350 KGLGGFSGFI 360 VSMLVAFLVS 370 TRKIHTTMSG 380 YQVLRSILQF 390 LATTDLTVNG 400 ISLCSSSDPS 410 LPALADFHQA 420 FPVVFLDPSG 430 HLNLCADVTA 440 STYRQVQHEA 450 QLSMALLDSR 460 ADDGFQLLLM 470 TPKPMIRAFD 480 HILHLCPLSR 490 LQAACHRLKL 500 WPELQDHGGD 510 YVSAALGPLT 520 TLLEQGLGSR 530 LHLLAHSRPP 540 VSEWDISQDP 550 PKHRDSRVLT 560 LGLLLRPEGL 570 TSVLELGPEA 580 DQPEAAAFRQ 590 FWGSRSELRR 600 FQDGAIREAV 610 VWEAASLAQK 620 RLIPHQVVTH 630 LLALHADIPD 640 TCVHYTGGFL 650 DALIQGLKET 660 SSTGEEALAA 670 AVRCYDDLSR 680 MLWGLEGLPL 690 TVSAVQGAHP 700 VLRYTEVFPP 710 TPARPACSFY 720 EHLRERASLL 730 PRPDKPCPAY 740 VEPMTVVCHL 750 EGSGQWPQDA 760 EAIRRVRAAF 770 QLRLAELLMQ 780 QHGLQCRATA 790 THTDVLKDGF 800 VFRIRVAYQR 810 EPQILRETRS 820 PEGMISLRDT 830 PASLRLERDT 840 KQLPLLTSAL 850 HGLQQQHPAF 860 SGVARLAKRW 870 VRAQLLGQEF 880 TDESLDLVAA 890 ALFLHPEPFT 900 PPSSPQVGFL 910 RFLFLVSTFD 920 WKNSPLIVNL 930 NNELTAEEQV 940 EIRSVFLATR 950 TQLPVMVIIT 960 PQDRKSSVWT 970 QNGPSPQILQ 980 RLVVLAAEAL 990 PVLEKQLMDP 1000 RGPGDIRTVF 1010 RPPLDMYDVL 1020 IRLTPRHIPR 1030 HRQAVDSPAA 1040 SFCRGLLSEP 1050 GPSSLMPVLG 1060 YDPPQLYLAQ 1070 LREAFGDLAL 1080 FFYDQHGGEV 1090 IGVLWKPTSF 1100 QPQPLKASNA 1110 KGRMVVSQGG 1120 ELVMVPNVEA 1130 ILEDFAILGE 1140 GLVQAVEARS ERWTV

Gene Ontology

Classification GO ID Description
Cellular Component GO:0000794 condensed nuclear chromosome
Cellular Component GO:0032545 CURI complex
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0032040 small-subunit processome
Cellular Component GO:0034456 UTP-C complex
Molecular Function GO:0003723 RNA binding
Biological Process GO:0042274 ribosomal small subunit biogenesis
Biological Process GO:0006364 rRNA processing
Biological Process GO:0006409 tRNA export from nucleus

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.