Search Results
Overview
| Uniprot ID | F1SEC0 |
|---|---|
| Protein Name | Dynactin subunit 3 |
| Gene Name | DCTN3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 50 | ALGNIASKRERVKIL |
Function
Part of the dynactin complex that activates the molecular motor dynein for ultra-processive transport along microtubules (PubMed:33734450, PubMed:36071160). Together with dynein is involved in spindle assembly and cytokinesis (By similarity)
Protein Sequence
10
MAGVTDVQRL
20
QARLEELERW
30
VYGPGGSRGS
40
RKVADGLVKV
50
QVALGNIASK
60
RERVKILYKK
70
IEDLIKYLDP
80
EYMDRIAIPD
90
ASKLQFILAE
100
EQFILSQVAL
110
LEQVEALVPM
120
LDSAHIKAVP
130
EHAARLQRLA
140
QIHIQQQDQC
150
VEITEESKAL
160
LEEYNKTTML
170
LSKQFVQWDE
180
LLCQLEAAKQ
VKPAEE
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005813 | centrosome |
| Cellular Component | GO:0032154 | cleavage furrow |
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005869 | dynactin complex |
| Cellular Component | GO:0000776 | kinetochore |
| Cellular Component | GO:0030496 | midbody |
| Cellular Component | GO:0005819 | spindle |
| Biological Process | GO:0061640 | cytoskeleton-dependent cytokinesis |
| Biological Process | GO:0007017 | microtubule-based process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.