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Overview

Uniprot IDF1SES4
Protein NameProtein FRG1
Gene NameFRG1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
11 YSYVKSTKLVLKGTK
212 CEINYVKKFQSFQDH

Function

Binds to mRNA in a sequence-independent manner. May play a role in regulation of pre-mRNA splicing or in the assembly of rRNA into ribosomal subunits. May be involved in mRNA transport. May be involved in epigenetic regulation of muscle differentiation through regulation of activity of the histone-lysine N-methyltransferase KMT5B

Protein Sequence

10 MAEYSYVKST 20 KLVLKGTKTK 30 SKKKKSKEKK 40 RKREEDEETQ 50 LDIVGIWWTV 60 TNFGEISGTI 70 AIEMDKGTYI 80 HALDNGLFTL 90 GAPHKEVDEG 100 PSPPEQFTAV 110 KLSDSRIALK 120 SGYGKYLGIN 130 SDGLVVGRSD 140 AIGPREQWEP 150 VFQDGKMALL 160 ASNSCFIRCN 170 EAGDIEAKSK 180 TAGEEEMIKI 190 RSCAERETKK 200 KDDIPEEDKG 210 NVKQCEINYV 220 KKFQSFQDHK 230 LKVSKEDSKI 240 LKKARKDGFL 250 HETLLDRSDV YKPILFF

Gene Ontology

Classification GO ID Description
Cellular Component GO:0015030 Cajal body
Cellular Component GO:0071013 catalytic step 2 spliceosome
Cellular Component GO:0005730 nucleolus
Cellular Component GO:0055120 striated muscle dense body
Cellular Component GO:0030018 Z disc
Molecular Function GO:0051015 actin filament binding
Molecular Function GO:0003723 RNA binding
Biological Process GO:0007517 muscle organ development
Biological Process GO:0006364 rRNA processing

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.