Search Results

Overview

Uniprot IDF1SFF8
Protein NameAlpha-1,4 glucan phosphorylase
Gene NamePYGL
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
29 VENVAELKKGFNRHL
390 KIAALFPKDVDRLRR
42 HLHFTLVKDRNVATP
434 KIHSDIVKTQVFKDF
508 LREISNVKQENKLKF
514 VKQENKLKFSQFLEK
693 EDVAALDKKGYNAKE
78 TQQYYYEKCPKRVYY

Function

Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis

Protein Sequence

10 MAKPLTDQEK 20 RRQISIRGIV 30 GVENVAELKK 40 GFNRHLHFTL 50 VKDRNVATPR 60 DYFFALAHTV 70 RDHLVGRWIR 80 TQQYYYEKCP 90 KRVYYLSLEF 100 YIGRTLQNTM 110 INLGLQNACD 120 EAIYQLGLDM 130 EELEEIEEDA 140 GLGNGGLGRL 150 AACFLDSMAT 160 LGLAAYGYGI 170 RYEYGIFNQK 180 IRDGWQIEEA 190 DDWLRHGNPW 200 EKARPEFMLP 210 VHFYGRVEHT 220 EAGTKWVDTQ 230 VVLALPYDTP 240 VPGYLNNTVN 250 TMRLWSARAP 260 NDFNLRDFNV 270 GDYIQAVLDR 280 NLAENISRVL 290 YPNDNFFEGK 300 ELRLKQEYFV 310 VAATLQDVIR 320 RFKASKFGSS 330 DSAGTAFDAF 340 PDQAWGITQK 350 TFAYTNHTVL 360 PEALERWPVE 370 LVEKLLPRHL 380 QIIYEINQKH 390 LDKIAALFPK 400 DVDRLRRMSL 410 IEEEGGKRIN 420 MAHLCIVGSH 430 AVNGVAKIHS 440 DIVKTQVFKD 450 FSELEPDKFQ 460 NKTNGITPRR 470 WLLLCNPGLA 480 ELIAEKIGED 490 YVKDLSQLTK 500 LHHFLGDDVF 510 LREISNVKQE 520 NKLKFSQFLE 530 KEYKVKINPA 540 SMFDVQVKRI 550 HEYKRQLMNC 560 LHVITMYNRI 570 KKDPKKLFVP 580 RTVIIGGKAA 590 PGYHMAKLII 600 KLITSVAEVV 610 NNDPVVGSKL 620 KVIFLENYRV 630 SLAEKVIPAT 640 DLSEQISTAG 650 TEASGTGNMK 660 FMLNGALTIG 670 TMDGANVEMA 680 EEAGEENLFI 690 FGMRVEDVAA 700 LDKKGYNAKE 710 YYEALPELKL 720 AIDQIDKGFF 730 SPKQPDLFKD 740 LVNMLFHHDR 750 FKVFADYEAY 760 VKCQEKVSQL 770 YMNPKAWNTM 780 VLKNIAAAGK 790 FSSDRTIKEY 800 ARDIWNMEPS 810 DLKISLSSEP 820 SGGVHKANGK LDK

Gene Ontology

Classification GO ID Description
Molecular Function GO:0008184 glycogen phosphorylase activity
Molecular Function GO:0030170 pyridoxal phosphate binding
Biological Process GO:0005977 glycogen metabolic process

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.