Search Results
Overview
| Uniprot ID | F1SGH5 |
|---|---|
| Protein Name | Pyruvate dehydrogenase E1 component subunit beta |
| Gene Name | PDHB |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 185 | PWSSEDAKGLIKSAI |
| 228 | DFLIPIGKAKIERQG |
| 355 | KDIIFAIKKTLNI** |
Function
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2
Protein Sequence
10
MAVVAGLVRR
20
PLEQVSGLLL
30
RRRFHRTAPA
40
ALQVTVRDAI
50
NQGMDEELER
60
DEKVFLLGEE
70
VAQYDGAYKV
80
SRGLWKKYGD
90
KRIIDTPISE
100
MGFAGIAVGA
110
AMAGLRPICE
120
FMTFNFSMQA
130
IDQVINSAAK
140
TYYMSGGLQS
150
VPIVFRGPNG
160
ASAGVAAQHS
170
QCFAAWYGHC
180
PGLKVVSPWS
190
SEDAKGLIKS
200
AIRDNNPVVV
210
LENELMYGVP
220
FELPAEAQSK
230
DFLIPIGKAK
240
IERQGTHITI
250
VSHSRPVGHC
260
LEAATVLSKE
270
GIECEVINMR
280
TIRPMDIETI
290
EASVMKTTHL
300
ITVEGGWPQF
310
GIGAEICARI
320
MEGPAFNFLD
330
APAVRVTGAD
340
VPMPYAKILE
350
DNSVPQVKDI
360
IFAIKKTLNI
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Cellular Component | GO:0045254 | pyruvate dehydrogenase complex |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0004739 | pyruvate dehydrogenase (acetyl-transferring) activity |
| Biological Process | GO:0006006 | glucose metabolic process |
| Biological Process | GO:0006086 | pyruvate decarboxylation to acetyl-CoA |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.