Search Results
Overview
| Uniprot ID | F1SGM1 |
|---|---|
| Protein Name | Proteasome activator complex subunit 1 |
| Gene Name | PSME1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 109 | GPVNCNEKIVVLLQR |
| 187 | ERGDAVAKAAKQPHV |
| 35 | LLGSYFPKKISELDA |
Function
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome
Protein Sequence
10
MATLRVQPEA
20
QAKVDVFRED
30
LCTKTENLLG
40
SYFPKKISEL
50
DAFLKEPALN
60
EANLSNLKAP
70
LDIPVPDPVK
80
EKEKEERKKQ
90
QEKEDKDEKK
100
KGEDEDKGPP
110
CGPVNCNEKI
120
VVLLQRLKPE
130
IKDVIEQLNL
140
VTTWLQLQIP
150
RIEDGNNFGV
160
AVQEKVFELM
170
TALHTKLEGF
180
HTQISKYFSE
190
RGDAVAKAAK
200
QPHVGDYRQL
210
VHELDEAEYR
220
DIRLMVMEIR
230
NAYVFPLVEP
240
THWVIWTLSC
250
WLVQSSRMSS
260
RWQSKSTRCW
270
WARPSSKAPT
280
ICRDSSQSLH
ITLK
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0008537 | proteasome activator complex |
| Molecular Function | GO:0061133 | endopeptidase activator activity |
| Biological Process | GO:2000045 | regulation of G1/S transition of mitotic cell cycle |
| Biological Process | GO:0061136 | regulation of proteasomal protein catabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.