Search Results
Overview
| Uniprot ID | F1SGM3 |
|---|---|
| Protein Name | Proteasome activator complex subunit 2 |
| Gene Name | PSME2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 15 | RLSGEARKQVDVFRQ |
| 169 | LERVNAVKTKVEAFQ |
| 171 | RVNAVKTKVEAFQTT |
Function
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome
Protein Sequence
10
MAKPCGVRLS
20
GEARKQVDVF
30
RQNLFQEAEE
40
FLYRFLPQKI
50
IYLSQLLQED
60
SLNVTDLTSL
70
RAPLDIPIPD
80
PPPKDDEMET
90
DKQEKKEGKR
100
GRGRDLNLLF
110
LTVPKCGFLP
120
GNEKILALLG
130
LVKPEVWTLK
140
EKCILVITWI
150
QHLIPKIEDG
160
NDFGVAVQEK
170
VLERVNAVKT
180
KVEAFQTTIS
190
KYFSERGDAV
200
AKASKETHVM
210
DYRALVHERD
220
EAAHGELRAM
230
VLDLRAFYAE
240
LYHIISSNLE
250
KIVNPKGEEK
PSMY
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0008537 | proteasome activator complex |
| Molecular Function | GO:0061133 | endopeptidase activator activity |
| Molecular Function | GO:0042802 | identical protein binding |
| Biological Process | GO:2000045 | regulation of G1/S transition of mitotic cell cycle |
| Biological Process | GO:0061136 | regulation of proteasomal protein catabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.