Search Results
Overview
| Uniprot ID | F1SGN8 |
|---|---|
| Protein Name | GMP reductase |
| Gene Name | GMPR2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 238 | SSEMAMKKYAGGVAE |
| 259 | KTVEVPFKGAVEHTI |
Function
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
Protein Sequence
10
MPHIDNDVKL
20
DFKDVLLRPK
30
RSTLKSRSEV
40
DLTRSFSFRN
50
SKQMYTGIPI
60
IAANMDTVGT
70
FEMAKVLCKF
80
SLFTAVHKHY
90
SLEQWKEFAS
100
QNPDCLEHTA
110
SSVSGPKNAD
120
WMVLSQAGNV
130
VTGEMVEELI
140
LSGADIIKVG
150
IGPGSVCTTR
160
KKTGVGYPQL
170
SAVMECADAA
180
HGLKGHIISD
190
GGCSCPGDVA
200
KAFGAGADFV
210
MLGGMLAGHS
220
ESGGELIERN
230
GKKYKLFYGM
240
SSEMAMKKYA
250
GGVAEYRASE
260
GKTVEVPFKG
270
AVEHTIRDIL
280
GGIRSTCTYV
290
GAAKLKELSR
300
RTTFIRVTQQ
VNPIFSDES
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:1902560 | GMP reductase complex |
| Molecular Function | GO:0003920 | GMP reductase activity |
| Molecular Function | GO:0046872 | metal ion binding |
| Biological Process | GO:0006144 | purine nucleobase metabolic process |
| Biological Process | GO:0006163 | purine nucleotide metabolic process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.