Search Results

Overview

Uniprot IDF1SH97
Protein NameGuanine nucleotide-binding protein-like 3
Gene NameGNL3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
196 NWLNYLKKELPTVVF
236 KTEVCVGKEGLWKLL
443 ARSIQAIKGPRLAGS

Function

May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation

Protein Sequence

10 MKRPKLKKSS 20 KRMTCHKRYK 30 IQKKVREHHR 40 KLRKEAKKRG 50 RKKPRKDPGI 60 PNSAPFKEAL 70 LREAELRKQR 80 LEELKQQQKL 90 ERQKEQDKKR 100 KLETNPGVEL 110 SHKVLVKEEF 120 GRSKAKKAKS 130 SKQNPKKLYC 140 QELKKVIEAS 150 DVVLEVLDAR 160 DPLGCRCPQV 170 EEAIVKGRQK 180 RLVLVLNKSD 190 LVPTENLENW 200 LNYLKKELPT 210 VVFKASTDLK 220 DKGKRIKFVK 230 ERKKVAPFKT 240 EVCVGKEGLW 250 KLLGGFQEIY 260 GKAICVGVIG 270 FPNVGKSSII 280 NSLKQERICN 290 VGVSMGLTRC 300 MQVVPLDKQI 310 TLIDSPGFIA 320 SPLNSASALA 330 LRSPASIEVI 340 KPMEAASAIL 350 SHADARQVVL 360 KFTVPDFENS 370 LEFFTSFAQR 380 RGLHQKGGSP 390 NVEGAAKLLW 400 SEWTGASLGY 410 YCHPPTSWTL 420 SSHFNESIVT 430 DMKWGFNLEE 440 LEKNNARSIQ 450 AIKGPRLAGS 460 ILFQSSGLTN 470 GIIEEGDIPE 480 EPLKQKEQKQ 490 EEGEDYGDVD 500 TDQESVDKEG 510 DEKSSDTSPA 520 EEAFEAVPKG 530 SQAGEQSALS 540 FVMEKMTEED 550 DAYDFSTDYM L

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005730 nucleolus
Molecular Function GO:0005525 GTP binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.