Search Results
Overview
| Uniprot ID | F1SHE8 |
|---|---|
| Protein Name | Ribosome biogenesis protein WDR12 |
| Gene Name | WDR12 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 239 | NRPRKKQKTEQLGLT |
| 376 | LWDTRSCKAPLYDLA |
Function
Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome
Protein Sequence
10
MAQLQTRFFT
20
DNKKYAVDDV
30
PFSIPAASEI
40
ADLSNIINKL
50
LEAKNEFHKH
60
VEFDFLIKGQ
70
FLRMPLFKHM
80
ELENISSEEV
90
VELEYVEKYT
100
APQPEQCMFH
110
DDWISAIEGA
120
EEWILTGSYD
130
KTSRIWSSEG
140
KSIMTIVGHT
150
DVVKDVAWVK
160
KDSLSCLLLS
170
ASMDQTILLW
180
EWNVERNKVK
190
ALHCCRGHAG
200
SVDSIAVDST
210
GTRFCSGSWD
220
KMLKIWSTVP
230
TDEEDEMEES
240
TNRPRKKQKT
250
EQLGLTRTPI
260
VTLSGHKEAI
270
SSVLWSDAEE
280
ICSASWDHTI
290
GVWDVESGSL
300
KSTLTGNKVF
310
NCISYSPLCK
320
RLASGSTDRH
330
IRLWDPRTKD
340
GSLVSLSLTS
350
HTGWVTSVKW
360
SPTHEQQLIS
370
GSLDNIVKLW
380
DTRSCKAPLY
390
DLAAHEDKVL
400
SVDWTNTGLL
410
LSGGADNKLY
420
SYRYSPTTSH
VGA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0070545 | PeBoW complex |
| Cellular Component | GO:0030687 | preribosome, large subunit precursor |
| Molecular Function | GO:0043021 | ribonucleoprotein complex binding |
| Biological Process | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| Biological Process | GO:0051726 | regulation of cell cycle |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.