Search Results
Overview
| Uniprot ID | F1SHQ8 |
|---|---|
| Protein Name | Tubulin alpha chain |
| Gene Name | TUBA1B |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 146 | RLSVDYGKKSKLEFS |
| 309 | YRGDVVPKDVNAAIA |
| 319 | NAAIATIKTKRSIQF |
| 353 | VPGGDLAKVQRAVCM |
| 377 | AWARLDHKFDLMYAK |
| 384 | KFDLMYAKRAFVHWY |
| 43 | FSETGAGKHVPRAVF |
| 79 | PEQLITGKEDAANNY |
Function
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin
Protein Sequence
10
NACWELYCLE
20
HGIQPDGQMP
30
SDKTIGGGDD
40
SFNTFFSETG
50
AGKHVPRAVF
60
VDLEPTVIDE
70
VRTGTYRQLF
80
HPEQLITGKE
90
DAANNYARGH
100
YTIGKEIIDL
110
VLDRIRKLAD
120
QCTGLQGFLV
130
FHSFGGGTGS
140
GFTSLLMERL
150
SVDYGKKSKL
160
EFSIYPAPQV
170
STAVVEPYNS
180
ILTTHTTLEH
190
SDCAFMVDNE
200
AIYDICRRNL
210
DIERPTYTNL
220
NRLISQIVSS
230
ITASLRFDGA
240
LNVDLTEFQT
250
NLVPYPRIHF
260
PLATYAPVIS
270
AEKAYHEQLS
280
VAEITNACFE
290
PANQMVKCDP
300
RHGKYMACCL
310
LYRGDVVPKD
320
VNAAIATIKT
330
KRSIQFVDWC
340
PTGFKVGINY
350
QPPTVVPGGD
360
LAKVQRAVCM
370
LSNTTAIAEA
380
WARLDHKFDL
390
MYAKRAFVHW
400
YVGEGMEEGE
410
FSEAREDMAA
420
LEKDYEEFWN
LGHRAWKM
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005874 | microtubule |
| Molecular Function | GO:0005525 | GTP binding |
| Molecular Function | GO:0016787 | hydrolase activity |
| Molecular Function | GO:0005200 | structural constituent of cytoskeleton |
| Biological Process | GO:0007017 | microtubule-based process |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.