Search Results

Overview

Uniprot IDF1SJ07
Protein NamePleckstrin
Gene NamePLEK
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
247 EFRGVIIKQGCLLKQ

Function

Major protein kinase C substrate of platelets

Protein Sequence

10 MEPKRIREGY 20 LVKKGSMFNT 30 WKPMWVILLE 40 DGIEFYKKKS 50 DNSPKGMIPL 60 KGSTLTSPCQ 70 DFGKRMFVFK 80 ITTTKQQDHF 90 FQAAFLEERD 100 GWVRDIKKAI 110 KCIEGGQKFA 120 RKSTRRSIRL 130 PETIDLGALY 140 LSMKDTEKGI 150 KELNLEKDKK 160 VFNHCFTGNC 170 VIDWLLSNNS 180 VRNRQEGIMI 190 ASSLLNEGYL 200 QPAGDLSKSA 210 VDGTAENPFL 220 DNADAFYYFP 230 DSGFFCEDNS 240 SDDDVILKEE 250 FRGVIIKQGC 260 LLKQGHRRKN 270 WKVRKFILRE 280 DPAYLHYYDP 290 AGGEDPLGAI 300 HLRGCVVTSV 310 ESNTDGRRSE 320 EENLFEIITA 330 DEVHYFLQAA 340 NPKERTEWIK 350 AIQVASRTGK

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005886 plasma membrane
Biological Process GO:0030036 actin cytoskeleton organization
Biological Process GO:0035556 intracellular signal transduction
Biological Process GO:0002576 platelet degranulation
Biological Process GO:0030836 positive regulation of actin filament depolymerization
Biological Process GO:0044089 positive regulation of cellular component biogenesis
Biological Process GO:0070493 thrombin-activated receptor signaling pathway

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.