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Overview

Uniprot IDF1SJ72
Protein NameSnurportin-1
Gene NameSNUPN
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
34 RLSQYKSKYSSLEQS

Function

Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs

Protein Sequence

10 MEELSQALAS 20 SFSVSQDLNS 30 TAAPHPRLSQ 40 YKSKYSSLEQ 50 SERRRRLLEL 60 QKSKRQDYVN 70 HARRLAENDW 80 TGMESEEEEE 90 KKDDEEMDID 100 IGKKLPKHYA 110 NQLMLSEWLI 120 DVPSDLGQEW 130 IVVVCPVGKR 140 ALIVASRGST 150 SAYTKSGYCV 160 NRFSSLLPGG 170 NRRNSTTAKD 180 YTILDCIYSE 190 VNQTYYVLDV 200 MCWRGHPFYD 210 CQFKFVGLKN 220 FPCTPESLCE 230 VLSMDFPFEV 240 DGLLFYHKQT 250 HYSPGSTPLV 260 GWLRPYMVSD 270 VLGVAVPAGP 280 LTTKPEYAGH 290 QLQQIIEHKR 300 SQREGLKEKL 310 THKASENGCY 320 ELEHLSTPKL 330 KSPPQSLDPP GSLMEN

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005737 cytoplasm
Biological Process GO:0006606 protein import into nucleus
Biological Process GO:0061015 snRNA import into nucleus
Cellular Component GO:0005634 nucleus
Molecular Function GO:0061608 nuclear import signal receptor activity
Molecular Function GO:0003723 RNA binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.