Search Results
Overview
| Uniprot ID | F1SJG9 |
|---|---|
| Protein Name | Pumilio homolog 3 |
| Gene Name | PUM3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 211 | GDLVELSKAKYSRNI |
| 566 | KWLIEQDKKMKESGR |
Function
Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells
Protein Sequence
10
MMEVKGKKKF
20
TGKGTKTSQE
30
KNRFHKNNGS
40
GSSKTFPQKV
50
VKEGEPKITS
60
KNFEKSATKP
70
GKKGVKQFKN
80
KQQGDKIPKN
90
KFQQGNKFNR
100
KRKIQPDSKN
110
DGSAAKKPKW
120
DEFKKKKKEL
130
KQSRQLSDKA
140
NYDIVVRAKQ
150
IWEILRRKDC
160
NKEKRVKLMS
170
DLQKLIQGKI
180
KTIAFAHDST
190
RVIQCYIQYG
200
TEEQRKQAFE
210
ELRGDLVELS
220
KAKYSRNIVK
230
KFLMYGNKAQ
240
IAEIMRSFKG
250
HVRKMLRHAE
260
ASAIVEYAYN
270
DKAILEQRNM
280
LTEELYGNTF
290
QLYKSADCPT
300
LDKVLEVQPE
310
KLELIMDEMK
320
QILTPMAQKE
330
AVIKHSLVHK
340
VFLDFFTHAP
350
PKLRSEMIEA
360
IREAVIYLAH
370
THDGARVAMH
380
CLWHGTPKDR
390
KVIVKTMKTY
400
VEKVANGQYS
410
HLVLLAAFDC
420
IDDTKLVKQI
430
IISEIINSLP
440
NIVNDKYGRK
450
VLLYLLSPRD
460
PAHTVREIIE
470
VLQKGDGNAH
480
SKKDTEIRRR
490
ELLESISPAL
500
LSYLQGHAQE
510
VMLDKSACVL
520
VSDILGAAIG
530
DVQPAMNAIA
540
SLAAAELHPG
550
GKDGELHIAE
560
HPAGHLVLKW
570
LIEQDKKMKE
580
SGREGCFAKT
590
LVEHVGMKNL
600
KSWASVNRGA
610
IILSSLLQSS
620
DQEVANEVKA
630
GLKSLIPTLE
640
KNKNTSKGIE
MLLEKLTA
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005694 | chromosome |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Molecular Function | GO:0003677 | DNA binding |
| Molecular Function | GO:0003729 | mRNA binding |
| Biological Process | GO:0006417 | regulation of translation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.