Search Results
Overview
| Uniprot ID | F1SJP7 |
|---|---|
| Protein Name | Essential MCU regulator, mitochondrial |
| Gene Name | SMDT1 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 59 | RSGAILPKPVKMSFG |
Function
Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria
Protein Sequence
10
MASRAARWLA
20
LAPVRFGAFR
30
SGLSLRKGGD
40
VAAGQGHPGR
50
NLVPSRSVIV
60
TRSGAILPKP
70
VKMSFGLLRV
80
FSIVIPFLYV
90
GTLISKNFAA
100
LLEEHDIFVP
EDDDDDD
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:1990246 | uniplex complex |
| Molecular Function | GO:0099103 | channel activator activity |
| Molecular Function | GO:0030674 | protein-macromolecule adaptor activity |
| Biological Process | GO:0036444 | calcium import into the mitochondrion |
| Biological Process | GO:0072732 | cellular response to calcium ion starvation |
| Biological Process | GO:0051560 | mitochondrial calcium ion homeostasis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.