Search Results
Overview
| Uniprot ID | F1SJQ4 |
|---|---|
| Protein Name | Polymerase delta-interacting protein 3 |
| Gene Name | POLDIP3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 132 | TPALKLTKTIQVPQQ |
| 307 | VAEVVFVKKDDAITA |
Function
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex
Protein Sequence
10
MLFSVLNARP
20
GVGGIRSRVG
30
IQQSLLSQPA
40
RTATFQQRFD
50
ARQKIGLSDA
60
RLKLGVKDAR
70
EKLLQKDARF
80
RIKGKVQDAR
90
EMLNSRKQQS
100
TVPQKPRQVA
110
DAREKISLKR
120
NSPAAFMSPP
130
IGTVTPALKL
140
TKTIQVPQQK
150
AMAPVHAHPA
160
GMRINVVNNH
170
QAKQNLYDLD
180
EDDDVAPIPS
190
KQMKFVAPGN
200
FLHHVAGLSS
210
SKLSMSKALP
220
LTKVVQNDAY
230
TAPALPSSVR
240
TKALTNMSRT
250
LVNKEEPPKE
260
LPPAEPVLSP
270
LEGTKMTVNN
280
LHPRVTEEDI
290
VELFCVCGAL
300
KRARLVHPGV
310
AEVVFVKKDD
320
AITAYKKYNN
330
RCLDGQPMKC
340
NLHMNGNVIT
350
SDQPILLRLS
360
DSPSVKKESE
370
LPRRVNSAGS
380
SNPPAEVDPD
390
TILKALFKSS
400
GASVTTQPTE
FKIKL
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005737 | cytoplasm |
| Cellular Component | GO:0016607 | nuclear speck |
| Molecular Function | GO:0003723 | RNA binding |
| Biological Process | GO:0016973 | poly(A)+ mRNA export from nucleus |
| Biological Process | GO:0006417 | regulation of translation |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.