Search Results
Overview
| Uniprot ID | F1SKE2 |
|---|---|
| Protein Name | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 |
| Gene Name | PLOD2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 206 | KIYIDPLKREALNIT |
| 351 | NIKVFFDKAKHEITT |
| 353 | KVFFDKAKHEITTIK |
| 406 | LTNPRTLKILIEQNR |
| 414 | ILIEQNRKIIAPLVT |
| 91 | NTIGGGQKVRLMKEV |
Function
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links
Protein Sequence
10
MGWCTIRPQQ
20
LLLLVVLVLQ
30
PWNSCLGADS
40
EKPSIIPTDK
50
LLVITVATKE
60
SDGFHRFMQS
70
AKYFNYTVKV
80
LGQGEEWRGG
90
DGINTIGGGQ
100
KVRLMKEVME
110
NYANQEDLII
120
LFTECFDVIF
130
AGGPEEVLKK
140
FQKSNHKVVF
150
SADGILWPDK
160
RLADKYPIVH
170
IGKRYLNSGG
180
FIGYAPYINR
190
IVQQWNLQDN
200
DDDQLFYTKI
210
YIDPLKREAL
220
NITLDHKCKI
230
FQTLNGAVDE
240
VVLKFENGKA
250
RAKNVFYETL
260
PVAINGNGPT
270
KILLNYFGNY
280
VPNAWTQDNG
290
CTLCDVDTID
300
LSAVDVHPNV
310
TIGVFIEQPT
320
PFLPRFLDTL
330
LTLDYPKEAL
340
KLFIHNKEVY
350
HEKNIKVFFD
360
KAKHEITTIK
370
IVGPEENLSQ
380
AEARNMGMDF
390
CRQDENCNYY
400
FSVDADVVLT
410
NPRTLKILIE
420
QNRKIIAPLV
430
TRHGKLWSNF
440
WGALSPDGYY
450
ARSEDYVDIV
460
QGNRVGIWNV
470
PYMANVYLIK
480
GKTLRSEMNE
490
RNYFVRDKLD
500
PDMALCRNAR
510
EMTLQREKDS
520
PTPETFQMLS
530
PPKGVFMYVS
540
NRHEFGRLLS
550
TANYNISHYH
560
NDLWQIFENP
570
VDWKEKYINR
580
DYSKIFTENI
590
VEQPCPDVFW
600
FPIFSEKACD
610
ELVEEMEHYG
620
QWSGGKHHDS
630
RISGGYENVP
640
TDDIHMKQID
650
LENVWLHFIR
660
EFIAPVTLKV
670
FAGYYTKGFA
680
LLNFVVKYSP
690
ERQRSLRPHH
700
DASTFTINIA
710
LNNVGEDFQG
720
GGCKFLRYNC
730
SIESPRKGWS
740
FMHPGRLTHL
750
HEGLPVKNGT
760
RYIAVSFIDP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0031012 | extracellular matrix |
| Cellular Component | GO:0005615 | extracellular space |
| Cellular Component | GO:0005794 | Golgi apparatus |
| Cellular Component | GO:0030867 | rough endoplasmic reticulum membrane |
| Molecular Function | GO:0005506 | iron ion binding |
| Molecular Function | GO:0031418 | L-ascorbic acid binding |
| Molecular Function | GO:0008475 | procollagen-lysine 5-dioxygenase activity |
| Biological Process | GO:0032964 | collagen biosynthetic process |
| Biological Process | GO:0030199 | collagen fibril organization |
| Biological Process | GO:0046947 | hydroxylysine biosynthetic process |
| Biological Process | GO:0001666 | response to hypoxia |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.