Search Results

Overview

Uniprot ID	F1SKT8
Protein Name	Peptidylprolyl isomerase domain and WD repeat-containing protein 1
Gene Name	PPWD1
Organism	Sus scrofa

Kla Sites from experimental identification

Position	Flanking peptide
13	GSDSQLSKRRRRVPE
294	CFSPDGKKIATIGSD
65	ATLAKKRKVLEFERV

Function

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be involved in pre-mRNA splicing

Protein Sequence

10 MAAESGSDSQ 20 LSKRRRRVPE 30 EPEKTELSER 40 ELAVAVAVTQ 50 ENEEESEERW 60 VGPLPVEATL 70 AKKRKVLEFE 80 RVYLDNLPSA 90 SMYERSYMHR 100 DVITHVVCTK 110 TDFIITASHD 120 GHVKFWKKIE 130 EGIEFVKHFR 140 SHLGIIESIA 150 VSSEGALFCS 160 VGDDKAMKVF 170 DVVNFDMINM 180 LKLGYFPGQC 190 EWIYCPGDAI 200 SSVAASEKST 210 GKIFIYDGRG 220 DNQPLHIFDK 230 LHTSPLTQIR 240 LNPIYKAVVS 250 SDKSGMIEYW 260 TGPPHEYKFP 270 KNVNWEYKTD 280 TDLYEFAKCK 290 AYPTSICFSP 300 DGKKIATIGS 310 DRKVRIFRFL 320 TGKLMRVFDE 330 SLSMFTELQQ 340 MRQQLPDMEF 350 GRRMAVEREL 360 EKVDAVRLIN 370 IVFDETGHFV 380 LYGTMLGIKV 390 INVETNRCVR 400 ILGKQENIRV 410 MQLALFQGIA 420 KKHRAATTIE 430 MKASENPVLQ 440 NIQADPTVVC 450 TSFKKNRFYM 460 FTKREPEDTK 470 SADSDRDVFN 480 ERPSKEEVMA 490 ATQAEGPKRV 500 SDSAIIHTSM 510 GDIHIKLFPV 520 ECPKTVENFC 530 VHSRNGYYNG 540 HTFHRIIKGF 550 MIQTGDPTGT 560 GMGGESIWGG 570 EFEDEFHSTL 580 RHDRPYTLSM 590 ANAGSNTNGS 600 QFFITVVPTP 610 WLDNKHTVFG 620 RVTKGMEVVQ 630 RISNVKVNPK 640 TDKPYEDVSI INITVK

Gene Ontology

Classification	GO ID	Description
Cellular Component	GO:0071013	catalytic step 2 spliceosome
Cellular Component	GO:0016604	nuclear body
Molecular Function	GO:0003755	peptidyl-prolyl cis-trans isomerase activity
Biological Process	GO:0006397	mRNA processing
Biological Process	GO:0008380	RNA splicing

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.