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Overview

Uniprot IDF1SLR1
Protein NameNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Gene NameNDUFA8
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
128 MLCRWEEKDPRRCLE
239 EGDLKPAKHGSRLFF
96 DLKVQEVKVSSSVLK

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Protein Sequence

10 MTTGGMGGAE 20 AKSRPQTPRN 30 FLALRTLCVS 40 RLDGARRLRA 50 AAAHAQTLGG 60 PSAVGRGVQG 70 DPGDATSGIS 80 SVRATAIMPG 90 IVELPTLEDL 100 KVQEVKVSSS 110 VLKAAAHHYG 120 AQCDKPNKEF 130 MLCRWEEKDP 140 RRCLEEGKLV 150 NQCALDFFRQ 160 IKRHCAEPFT 170 EYWTCIDYSG 180 LQLFRHCRKQ 190 QAKFDECVLD 200 KLGWVRPDLG 210 ELSKVTKVKT 220 DRPLPENPYH 230 SRARPEPNPE 240 AEGDLKPAKH GSRLFFWTM

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005758 mitochondrial intermembrane space
Cellular Component GO:0045271 respiratory chain complex I
Biological Process GO:0006120 mitochondrial electron transport, NADH to ubiquinone

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.