Search Results
Overview
| Uniprot ID | F1SM98 |
|---|---|
| Protein Name | NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial |
| Gene Name | NDUFV2 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 136 | SILEAIQKKLGIKVG |
Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Parts of the peripheral arm of the enzyme, where the electrons from NADH are accepted by flavin mononucleotide (FMN) and then passed along a chain of iron-sulfur clusters by electron tunnelling to the final acceptor ubiquinone. Contains one iron-sulfur cluster
Protein Sequence
10
GRHVRNLHKT
20
AVQNGAGGAL
30
FVHRDTPENN
40
PDTPFDFTPE
50
NYKRIEAIVK
60
NYPEGHKAAA
70
VLPVLDLAQR
80
QNGWLPISAM
90
NKVAEILQVP
100
PMRVYEVATF
110
YTMYNRKPVG
120
KYHIQVCTTT
130
PCMLRNSDSI
140
LEAIQKKLGI
150
KVGETTPDKL
160
FTLIEVECLG
170
ACVNAPMVQI
180
NDNYYEDLTP
190
KDIEEIIDEL
200
KAGKIPKPGP
210
RSGRFSCEPA
220
GGLTSLTEPP
230
KGPGFGVQAG
L
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0045271 | respiratory chain complex I |
| Molecular Function | GO:0051537 | 2 iron, 2 sulfur cluster binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0008137 | NADH dehydrogenase (ubiquinone) activity |
| Molecular Function | GO:0016491 | oxidoreductase activity |
| Biological Process | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.