Search Results
Overview
| Uniprot ID | F1SMA9 |
|---|---|
| Protein Name | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit |
| Gene Name | SDHD |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 130 | VRGDALQKAAKAGLL |
Function
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). SDH also oxidizes malate to the non-canonical enol form of oxaloacetate, enol-oxaloacetate. Enol-oxaloacetate, which is a potent inhibitor of the succinate dehydrogenase activity, is further isomerized into keto-oxaloacetate
Protein Sequence
10
MTLSLQERHG
20
DSLEAQCSLR
30
CPRRRSSGPP
40
DLSGQTCSCL
50
SISPGPTTPG
60
WCGVQHIHLS
70
PSHQASSKAA
80
SLHWTGERVV
90
SVLLLGLLPA
100
AYLNPCSAMD
110
YSLAAALTLH
120
GHWGIGQVVT
130
DYVRGDALQK
140
AAKAGLLALS
150
AFTFAGLCYF
160
NYHDVGSAKL
170
LPCCGSSELL
ELIP
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Cellular Component | GO:0045273 | respiratory chain complex II (succinate dehydrogenase) |
| Molecular Function | GO:0020037 | heme binding |
| Molecular Function | GO:0046872 | metal ion binding |
| Molecular Function | GO:0048039 | ubiquinone binding |
| Biological Process | GO:0006121 | mitochondrial electron transport, succinate to ubiquinone |
| Biological Process | GO:0006099 | tricarboxylic acid cycle |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.