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Overview

Uniprot IDF1SMR6
Protein Name-
Gene NameZC3HC1
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
31 SPEGTPQKVRQLIDE

Function

Required for proper positioning of a substantial amount of TPR at the nuclear basket (NB) through interaction with TPR

Protein Sequence

10 MAAPSEGPAF 20 AAGVEKNWSA 30 IVRSPEGTPQ 40 KVRQLIDEGI 50 APEEGSAEAK 60 DTSATFQPVN 70 GSPQAEEPPL 80 ESTSKEAFFS 90 RVETFSSLKW 100 AGKPPELSPL 110 VCAKYGWVTV 120 ECDMLKCSSC 130 QAFLCATLQP 140 AFDFDRYKER 150 CAELKKALCT 160 AHEKFCFWPD 170 SPSPDRFGML 180 PLDEPGVLVS 190 EFLDRFQSLC 200 HLDLQLPSLR 210 PEDLKTMCLT 220 EDKITLLLHL 230 LEDELDHRTD 240 ERKTAIKLGS 250 DIQVHVTACI 260 LSVCGWACSS 270 ALEPVQLSLI 280 TCSQCMRKVG 290 LWGFQQMESL 300 ADLDASFGLT 310 SSPVPGSEGR 320 PERFPLVPES 330 PRRMMTRSQD 340 ATFSPGSEQA 350 ERSPGPIVTR 360 TRSWDSSSPI 370 DRPEPEAASP 380 TTRTRPVTRS 390 MGTGDTAGLE 400 VPSSPLRRAK 410 RARLCSSSSS 420 DASPRGFFDP 430 TSQHRDWCPW 440 VNITLGKESK 450 ESGGAEVDAS 460 TPAEPGWRAV 470 LNSLLAHKQS 480 NQPAETDSMS 490 LSEKSRKVFR 500 IFRQWESLCS S

Gene Ontology

Classification GO ID Description
Cellular Component GO:0031965 nuclear membrane
Cellular Component GO:0044615 nuclear pore nuclear basket
Cellular Component GO:0005654 nucleoplasm
Cellular Component GO:0005634 nucleus
Molecular Function GO:0019901 protein kinase binding
Molecular Function GO:0008270 zinc ion binding

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.