Search Results
Overview
| Uniprot ID | F1SN58 |
|---|---|
| Protein Name | Sulfide:quinone oxidoreductase, mitochondrial |
| Gene Name | SQOR |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 134 | CIHTDNGKEISYRYL |
| 155 | QLDYEKIKGLPEGFD |
| 180 | RTVEKTWKALQDFKE |
| 241 | GAIFGVKKYADALQE |
Function
Catalyzes the oxidation of hydrogen sulfide with the help of a quinone, such as ubiquinone-10, giving rise to thiosulfate and ultimately to sulfane (molecular sulfur) atoms. Requires an additional electron acceptor; can use sulfite, sulfide or cyanide (in vitro). It is believed the in vivo electron acceptor is glutathione
Protein Sequence
10
MTSLATVASG
20
PRTRLFACFL
30
RLGTQQVSPL
40
QLHTGTNLAA
50
KNHYEVLVLG
60
GGSGGITMAA
70
RMKRRVGAEN
80
VAIVEPSERH
90
FYQPIWTLVG
100
AGIKQLSSSG
110
RPTASVIPSG
120
VEWIKARVVD
130
LNPDKNCIHT
140
DNGKEISYRY
150
LIIALGIQLD
160
YEKIKGLPEG
170
FDHPKIGSNY
180
SFRTVEKTWK
190
ALQDFKEGNA
200
IFTFPNTPVK
210
CAGAPQKIMY
220
LSEAYFRKTG
230
RRSKANIIFN
240
TSLGAIFGVK
250
KYADALQEII
260
RERNLTINYK
270
QNLIEVRADK
280
QEAVFENLDK
290
PGETQVISYE
300
MLHVTPPMSP
310
PDVLKTSPVA
320
DAAGWVDVDK
330
DTLQHKRYPN
340
VFGIGDCTNL
350
PTSKTAAAVA
360
AQSGVLDRTI
370
SLIMKNQTPT
380
KKYDGYTSCP
390
LVTGYNRVIL
400
AEFDYNAKPL
410
ETFPFDQSKE
420
RLSMYLMKAN
430
MMPFLYWNGM
440
LRGYWGGPAF
450
LRKLFHLGMS
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005739 | mitochondrion |
| Molecular Function | GO:0071949 | FAD binding |
| Molecular Function | GO:0106436 | glutathione-dependent sulfide quinone oxidoreductase activity |
| Molecular Function | GO:0048038 | quinone binding |
| Molecular Function | GO:0070224 | sulfide:quinone oxidoreductase activity |
| Biological Process | GO:0070221 | sulfide oxidation, using sulfide:quinone oxidoreductase |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.