Search Results
Overview
| Uniprot ID | F1SQT3 |
|---|---|
| Protein Name | Solute carrier family 25 member 3 |
| Gene Name | SLC25A3 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 204 | TLRDAAPKMYQEEGL |
| 212 | MYQEEGLKAFYKGVA |
| 245 | RTVEALYKFVVPKPR |
| 250 | LYKFVVPKPRSECSK |
| 293 | VSVLNKEKGSSASQV |
| 311 | LGFRGVWKGLFARII |
| 97 | RMQVDPNKYKGIFNG |
Function
Inorganic ion transporter that transports phosphate or copper ions across the mitochondrial inner membrane into the matrix compartment. Mediates proton-coupled symport of phosphate ions necessary for mitochondrial oxidative phosphorylation of ADP to ATP. Transports copper ions probably in the form of anionic copper(I) complexes to maintain mitochondrial matrix copper pool and to supply copper for cytochrome C oxidase complex assembly. May also play a role in regulation of the mitochondrial permeability transition pore (mPTP)
Protein Sequence
10
MFSSVAHLAR
20
ANPFNAPHLQ
30
LVQDGLAGPR
40
SSPDGPPGPP
50
RRTRNLAAAA
60
VEEYSCEYGS
70
MKFYALCGFG
80
GVLSCGLHTA
90
VVPLDLVKCR
100
MQVDPNKYKG
110
IFNGFSITLK
120
EDGVRGLAKG
130
WAPTFIGYSL
140
QGLCKFGFYE
150
VFKVLYSNML
160
GEENAYLWRT
170
SLYLAASASA
180
EFFADIALAP
190
MEAAKVRIQT
200
QPGYANTLRD
210
AAPKMYQEEG
220
LKAFYKGVAP
230
LWMRQIPYTM
240
MKFACFERTV
250
EALYKFVVPK
260
PRSECSKPEQ
270
LVVTFVAGYI
280
AGVFCAIVSH
290
PADSVVSVLN
300
KEKGSSASQV
310
LRRLGFRGVW
320
KGLFARIIMI
330
GTLTALQWFI
340
YDSVKVYFRL
350
PRPPPPEMPE
360
SLKKKLGYTQ
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005743 | mitochondrial inner membrane |
| Molecular Function | GO:0005315 | phosphate transmembrane transporter activity |
| Biological Process | GO:1990547 | mitochondrial phosphate ion transmembrane transport |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.