Search Results

Overview

Uniprot IDF1SQT3
Protein NameSolute carrier family 25 member 3
Gene NameSLC25A3
OrganismSus scrofa

Kla Sites from experimental identification

Position Flanking peptide
204 TLRDAAPKMYQEEGL
212 MYQEEGLKAFYKGVA
245 RTVEALYKFVVPKPR
250 LYKFVVPKPRSECSK
293 VSVLNKEKGSSASQV
311 LGFRGVWKGLFARII
97 RMQVDPNKYKGIFNG

Function

Inorganic ion transporter that transports phosphate or copper ions across the mitochondrial inner membrane into the matrix compartment. Mediates proton-coupled symport of phosphate ions necessary for mitochondrial oxidative phosphorylation of ADP to ATP. Transports copper ions probably in the form of anionic copper(I) complexes to maintain mitochondrial matrix copper pool and to supply copper for cytochrome C oxidase complex assembly. May also play a role in regulation of the mitochondrial permeability transition pore (mPTP)

Protein Sequence

10 MFSSVAHLAR 20 ANPFNAPHLQ 30 LVQDGLAGPR 40 SSPDGPPGPP 50 RRTRNLAAAA 60 VEEYSCEYGS 70 MKFYALCGFG 80 GVLSCGLHTA 90 VVPLDLVKCR 100 MQVDPNKYKG 110 IFNGFSITLK 120 EDGVRGLAKG 130 WAPTFIGYSL 140 QGLCKFGFYE 150 VFKVLYSNML 160 GEENAYLWRT 170 SLYLAASASA 180 EFFADIALAP 190 MEAAKVRIQT 200 QPGYANTLRD 210 AAPKMYQEEG 220 LKAFYKGVAP 230 LWMRQIPYTM 240 MKFACFERTV 250 EALYKFVVPK 260 PRSECSKPEQ 270 LVVTFVAGYI 280 AGVFCAIVSH 290 PADSVVSVLN 300 KEKGSSASQV 310 LRRLGFRGVW 320 KGLFARIIMI 330 GTLTALQWFI 340 YDSVKVYFRL 350 PRPPPPEMPE 360 SLKKKLGYTQ

Gene Ontology

Classification GO ID Description
Cellular Component GO:0005743 mitochondrial inner membrane
Molecular Function GO:0005315 phosphate transmembrane transporter activity
Biological Process GO:1990547 mitochondrial phosphate ion transmembrane transport

Reference

[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.