Search Results
Overview
| Uniprot ID | F1SQV8 |
|---|---|
| Protein Name | choline-phosphate cytidylyltransferase |
| Gene Name | PCYT1A |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 213 | LQRGYTAKELNVSFI |
| 239 | DKVKKKVKDVEEKSK |
| 251 | KSKEFVQKVEEKSID |
| 340 | PTNLSRHKAAAYDIS |
Function
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis
Protein Sequence
10
MDAQNSAKVN
20
TRKRRKEAPG
30
PNGAAEEDGI
40
PSKTPRCAVG
50
LREPAPFSDE
60
IEVDFSKPYV
70
RVTMEEASRG
80
TCERPVRVYA
90
DGIFDLFHSG
100
HARALMQAKN
110
LFPNTYLIVG
120
VMNENERYDA
130
VQHCRYVDEV
140
VRNAPWTLTP
150
EFLAEHRIDF
160
VAHDDIPYSS
170
AGSDDVYKHI
180
KEAGMFAPTQ
190
RTEGISTSDI
200
ITRIVRDYDV
210
YARRNLQRGY
220
TAKELNVSFI
230
NEKKYHLQER
240
VDKVKKKVKD
250
VEEKSKEFVQ
260
KVEEKSIDLI
270
QKWEEKSREF
280
IGSFLEMFGP
290
EGALKHMLKE
300
GKGRMLQAIS
310
PKQSPSSSPT
320
RERSPSPSFR
330
WPFSGKTSPP
340
SSPTNLSRHK
350
AAAYDISEDE
ED
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Molecular Function | GO:0004105 | choline-phosphate cytidylyltransferase activity |
| Cellular Component | GO:0005783 | endoplasmic reticulum |
| Cellular Component | GO:0005789 | endoplasmic reticulum membrane |
| Cellular Component | GO:0042587 | glycogen granule |
| Cellular Component | GO:0005634 | nucleus |
| Molecular Function | GO:0042802 | identical protein binding |
| Molecular Function | GO:0031210 | phosphatidylcholine binding |
| Biological Process | GO:0042100 | B cell proliferation |
| Biological Process | GO:0045190 | isotype switching |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.