Search Results
Overview
| Uniprot ID | F1SRM2 |
|---|---|
| Protein Name | Cytoplasmic 60S subunit biogenesis factor ZNF622 |
| Gene Name | ZNF622 |
| Organism | Sus scrofa |
Kla Sites from experimental identification
| Position | Flanking peptide |
|---|---|
| 294 | LIKYLGEKVGVGKIC |
Function
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit
Protein Sequence
10
MATYTCNTCR
20
VVLVDAEAQR
30
AHYKTDWHRY
40
NLRRKVAGMA
50
PVSAEGFQER
60
VRAQRALAEP
70
ESKGAATYCT
80
VCSKKFASFK
90
AYENHLKSRR
100
HVELEKRAVS
110
RKVAILNEKN
120
LEKGLGVDGV
130
DKDAVNAAIQ
140
QVIKAQPSTS
150
PKKAAPALEA
160
EFRSPVSVAA
170
GGRGAHQRDP
180
AEKPPRLQWF
190
EQQARKLAKQ
200
QGEEESEEEL
210
DDGDDWEDIE
220
SDEEVECEDG
230
EALDQEEEQD
240
AEEEEAGGSP
250
PLGAIPITDC
260
LFCPHHSSSL
270
VKNVAHMTKV
280
HSFFLPDVEY
290
LSDLKGLIKY
300
LGEKVGVGKI
310
CLWCNEKGKS
320
FYSTEAVQAH
330
MHDRSHCKLF
340
TDGDALLEFA
350
DFYDFRSSYP
360
DHKEGEDPDE
370
TEALPSEKPL
380
GYDDDTMELI
390
LPSGARVGHR
400
SLMRYYKQRF
410
GLSRAVAVAR
420
NQKAVGRVLQ
430
QYRALGWTGS
440
TGAALVRQRD
450
MQYVQRMKSK
460
WLLKMGVKNN
470
ATKQMHFRPQ
VMF
Gene Ontology
| Classification | GO ID | Description |
|---|---|---|
| Cellular Component | GO:0005829 | cytosol |
| Cellular Component | GO:0005730 | nucleolus |
| Cellular Component | GO:0005654 | nucleoplasm |
| Cellular Component | GO:0030687 | preribosome, large subunit precursor |
| Molecular Function | GO:0003676 | nucleic acid binding |
| Molecular Function | GO:1990275 | preribosome binding |
| Molecular Function | GO:0008270 | zinc ion binding |
| Biological Process | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress |
| Biological Process | GO:0043065 | positive regulation of apoptotic process |
| Biological Process | GO:0046330 | positive regulation of JNK cascade |
| Biological Process | GO:0042273 | ribosomal large subunit biogenesis |
Reference
[1] Fan S, Zhou R, Wen H, Ye H, Ma S et al.. Global profiling of protein lactylome in porcine granulosa cells.. J Ovarian Res 18(1):177. 2025 Aug 8. PMID: 40781717.